SCHEMBL28898577

SCHEMBL28898577

Cc1ccccc1C=CC1=NS(=O)(=O)Oc2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.40
NR1H3 Q13133 1/20 0.40
RAB9A P51151 5/20 0.38
CYP1A2 P05177 2/20 0.38
TSHR P16473 2/20 0.38
TP53 P04637 1/20 0.38
CYP2D6 P10635 1/20 0.38
THPO P40225 1/20 0.38
HIF1A Q16665 1/20 0.38
KDM4E B2RXH2 5/20 0.37
CYP2C19 P33261 1/20 0.37
ALDH1A1 P00352 4/20 0.36
LMNA P02545 4/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
GMNN O75496 1/20 0.36
PMP22 Q01453 1/20 0.36
NPC1 O15118 2/20 0.34
POLB P06746 2/20 0.34
GAA P10253 2/20 0.34
APOBEC3A P31941 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28898584 1.00 NR1H2 (0.40) NR1H2NR1H3RAB9ACYP1A2TSHR
SCHEMBL30024906 1.00 NR1H2 (0.40) NR1H2NR1H3RAB9ACYP1A2TSHR
SCHEMBL30025843 0.83 MAPT (0.38) RAB9ACYP1A2TP53KDM4ECYP2C19
SCHEMBL28898556 0.83 MAPT (0.38) RAB9ACYP1A2TP53KDM4ECYP2C19
SCHEMBL28898549 0.83 HSD11B1 (0.37) RAB9ANPC1ALPIMEN1KMT2A
SCHEMBL28898553 0.83 MAPT (0.38) RAB9ACYP1A2TP53KDM4ECYP2C19
SCHEMBL30025407 0.83 HSD11B1 (0.37) RAB9ANPC1ALPIMEN1KMT2A
SCHEMBL28898552 0.83 HSD11B1 (0.37) RAB9ANPC1ALPIMEN1KMT2A
SCHEMBL28898569 0.83 NR1H3 (0.44) NR1H3RAB9ACYP1A2CYP2D6KDM4E
SCHEMBL28898568 0.83 NR1H3 (0.44) NR1H3RAB9ACYP1A2CYP2D6KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109336845-B Optically active cyclopentane-3-imine and its derivative and preparation method 西华师范大学 2022-11-01 CN claimed
CN-109336845-B Optically active cyclopentane-3-imine and its derivative and preparation method 西华师范大学 2022-11-01 CN disclosed