Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 2/20 | 0.36 |
| ▸ | IL1RN | P18510 | 1/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8984790 | 0.83 | PNMT (0.46) | PNMTNPC1RAB9ASIGMAR1HTR7 | |
| SCHEMBL21580187 | 0.77 | PNMT (0.39) | PNMTNPC1RAB9AANPEPIL1RN | |
| SCHEMBL28945985 | 0.75 | PNMT (0.45) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL6524402 | 0.75 | PNMT (0.45) | PNMTNPC1RAB9AHTR7HTR2B | |
| Iodide SCHEMBL3382482 | 0.74 | PNMT (0.52) | PNMTNPC1RAB9AHTR7HTR2B | |
| Fluoride Ion SCHEMBL3384402 | 0.74 | PNMT (0.52) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL30274953 | 0.74 | PNMT (0.52) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hydrochloric Acid SCHEMBL3385861 | 0.74 | PNMT (0.52) | PNMTNPC1RAB9AHTR7HTR2B | |
| Bromide SCHEMBL3383744 | 0.74 | PNMT (0.52) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL29187306 | 0.74 | ADRA1A (0.45) | ADRA1AIDO1PDPK1SIGMAR1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106905133-B | Spiro-fluorene-indene diketone compound and preparation method and application thereof | 肇庆医学高等专科学校 | 2020-06-19 | — | — | CN | disclosed |