SCHEMBL28899271

SCHEMBL28899271

CCCCn1c2ccccc2c2ccc(C=O)cc21

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 2/20 0.58
PGR P06401 2/20 0.56
RORA P35398 2/20 0.56
RORC P51449 2/20 0.56
RORB Q92753 2/20 0.56
ALDH1A1 P00352 1/20 0.51
PSEN1 P49768 10/20 0.50
PSEN2 P49810 10/20 0.50
APH1B Q8WW43 10/20 0.50
NCSTN Q92542 10/20 0.50
APH1A Q96BI3 10/20 0.50
PSENEN Q9NZ42 10/20 0.50
CNR2 P34972 3/20 0.48
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5519249 0.94 PSEN1 (0.57) PTGER4PGRRORARORCRORB
SCHEMBL9019646 0.91 PTGER4 (0.69) PTGER4PGRRORARORCRORB
SCHEMBL31201905 0.91 PTGER4 (0.69) PTGER4PGRRORARORCRORB
SCHEMBL600436 0.87 PTGER4 (0.67) PTGER4PGRRORARORCRORB
SCHEMBL279067 0.87 PSEN1 (0.49) PTGER4PSEN1PSEN2APH1BNCSTN
SCHEMBL278612 0.87 PSEN1 (0.49) PTGER4PSEN1PSEN2APH1BNCSTN
SCHEMBL5153575 0.86 PTGER4 (0.66) PTGER4PSEN1PSEN2APH1BNCSTN
SCHEMBL31174405 0.86 PTGER4 (0.66) PTGER4PSEN1PSEN2APH1BNCSTN
SCHEMBL4821945 0.86 PTGER4 (0.66) PTGER4PSEN1PSEN2APH1BNCSTN
SCHEMBL28446594 0.86 PTGER4 (0.66) PTGER4PSEN1PSEN2APH1BNCSTN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111635354-B Multi-ion difference detection fluorescent probe with carbazole Schiff base as recognition receptor 陕西科技大学 2022-01-25 CN disclosed
CN-111635354-A Multi-ion difference detection fluorescent probe with carbazole Schiff base as recognition receptor 陕西科技大学 2020-09-08 CN disclosed