SCHEMBL278612

SCHEMBL278612

CCCCCCn1c2cc(C=O)ccc2c2ccc(C=O)cc21

nearest known ligand 0.49

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PSEN1 P49768 19/20 0.49
PSEN2 P49810 19/20 0.49
APH1B Q8WW43 19/20 0.49
NCSTN Q92542 19/20 0.49
APH1A Q96BI3 19/20 0.49
PSENEN Q9NZ42 19/20 0.49
PTGER4 P35408 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL279067 1.00 PSEN1 (0.49) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL5519249 0.93 PSEN1 (0.57) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL28615487 0.88 PTGER4 (0.56) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL6775173 0.88 PTGER4 (0.56) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL29794198 0.88 PTGER4 (0.56) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL29794182 0.88 PTGER4 (0.56) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL6279947 0.88 PTGER4 (0.56) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL6281257 0.88 PTGER4 (0.56) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL6275738 0.88 PTGER4 (0.56) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL29808759 0.88 PTGER4 (0.56) PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260028317-A1 EFFICIENT PROCEDURE FOR THE SYNTHESIS OF HYDRAZONE-LINKED TETRAHEDRAL NANOCAGES UNIV VERMONT (US) 2026-01-29 US disclosed
WO-2024015528-A1 EFFICIENT PROCEDURE FOR THE SYNTHESIS OF HYDRAZONE-LINKED TETRAHEDRAL NANOCAGES UNIVERSITY OF VERMONT (US) 2024-01-18 WO disclosed
US-8134143-B2 2,7-carbazolenevinylene derivatives as novel materials in producing organic based electronic devices NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2012-03-13 US disclosed
EP-1660450-A4 MONOMERS, OLIGOMERS AND POLYMERS OF 2-FUNCTIONALIZED AND 2,7-DIFUNCTIONALIZED CARBAZOLES UNIV LAVAL (CA) 2009-07-29 EP disclosed
US-20070176163-A1 2,7-Carbazolenevinylene derivatives as novel materials in producing organic based electronic devices NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2007-08-02 US disclosed
US-20070069197-A1 Monomers, oligomers and polymers of 2-functionalized and 2,7-difunctionalized carbzoles UNIVERSITE LAVAL (CA) 2007-03-29 US disclosed
EP-1660450-A1 MONOMERS, OLIGOMERS AND POLYMERS OF 2-FUNCTIONALIZED AND 2,7-DIFUNCTIONALIZED CARBAZOLES Université Laval (CA) 2006-05-31 EP disclosed
WO-2005016882-A1 MONOMERS, OLIGOMERS AND POLYMERS OF 2-FUNCTIONALIZED AND 2,7-DIFUNCTIONALIZED CARBAZOLES UNIVERSITE LAVAL (CA) 2005-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070069197-A1 Monomers, oligomers and polymers of 2-functionalized and 2,7-difunctionalized carbzoles TELO2, DNMT1, DDT PSEN1 4166/4885PSEN2 3936/4885APH1B 2571/4885
US-20260028317-A1 EFFICIENT PROCEDURE FOR THE SYNTHESIS OF HYDRAZONE-LINKED TETRAHEDRAL NANOCAGES FTH1, AOC2, CCRL2 PSEN1 4019/4885PSEN2 4182/4885APH1B 4688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.