Methacrylic Acid

Methacrylic Acid

SCHEMBL28899440

C=C(C)C(=O)O.O=C(O)CNC(CC(=O)O)C(=O)O

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.42
CA2 P00918 1/20 0.36
CA4 P22748 1/20 0.36
GNPAT O15228 1/20 0.36
FNTA P49354 2/20 0.34
FNTB P49356 2/20 0.34
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
THRB P10828 1/20 0.33
ALOX15 P16050 1/20 0.33
NFKB1 P19838 1/20 0.33
PTGS2 P35354 1/20 0.33
THPO P40225 1/20 0.33
RECQL P46063 1/20 0.33
BLM P54132 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MME P08473 3/20 0.33
GRN P28799 1/20 0.33
SORT1 Q99523 1/20 0.33
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL7744038 0.88 CA2 (0.40) CA2CA4GNPATFNTAFNTB
SCHEMBL472192 0.86 CA2 (0.44) CA2CA4GNPATMAPTSMN1; SMN2
SCHEMBL20521 0.86 CA2 (0.44) CA2CA4GNPATMAPTSMN1; SMN2
SCHEMBL28623751 0.84 CA2 (0.42) CA2CA4GNPATMAPTSMN1; SMN2
Phosphine SCHEMBL27579074 0.84 CA2 (0.42) CA2CA4GNPATMAPTSMN1; SMN2
SCHEMBL10801445 0.84 CA2 (0.42) CA2CA4GNPATMAPTSMN1; SMN2
SCHEMBL28372032 0.84 CA2 (0.42) CA2CA4GNPATMAPTSMN1; SMN2
SCHEMBL28623754 0.84 CA2 (0.42) CA2CA4GNPATMAPTSMN1; SMN2
SCHEMBL10801439 0.84 CA2 (0.42) CA2CA4GNPATMAPTSMN1; SMN2
SCHEMBL18794824 0.79 CA2 (0.39) CA2CA4GNPATMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111569849-A Immobilized metal chelate chromatography medium and preparation method and application thereof 北京石油化工学院 2020-08-25 CN disclosed