Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 4/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19432844 | 0.98 | TSHR (0.36) | DNM1SMPD1FDPSTSHRTHRB | |
| SCHEMBL25517514 | 0.98 | TSHR (0.36) | DNM1SMPD1FDPSTSHRTHRB | |
| SCHEMBL20844268 | 0.96 | OPRM1 (0.37) | DNM1SMPD1FDPSTSHRTHRB | |
| SCHEMBL17800821 | 0.83 | OPRM1 (0.44) | OPRM1LMNASPHK1 | |
| SCHEMBL28503157 | 0.83 | DNM1 (0.41) | DNM1SMPD1FDPSTSHRTHRB | |
| SCHEMBL28453949 | 0.83 | OPRM1 (0.44) | OPRM1LMNASPHK1 | |
| SCHEMBL11897490 | 0.83 | OPRM1 (0.44) | OPRM1LMNASPHK1 | |
| SCHEMBL372711 | 0.83 | OPRM1 (0.44) | OPRM1LMNASPHK1 | |
| SCHEMBL28516883 | 0.83 | DNM1 (0.41) | DNM1SMPD1FDPSTSHRTHRB | |
| SCHEMBL26063991 | 0.83 | DNM1 (0.41) | DNM1SMPD1FDPSTSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115414536-A | Gene elution balloon and preparation method and application thereof | 苏州中天医疗器械科技有限公司 | 2022-12-02 | — | — | CN | disclosed |