SCHEMBL28899699

SCHEMBL28899699

O=C1NNCc2ccc3ncncc3c21

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MKNK2 Q9HBH9 5/20 0.33
MKNK1 Q9BUB5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28449989 0.67 AHR (0.39)
SCHEMBL17292541 0.66 CYP11B1 (0.37)
SCHEMBL16681713 0.64 EGFR (0.33)
SCHEMBL13154670 0.63 CHRNB2 (0.33) MKNK1
SCHEMBL29288694 0.62 CES1 (0.41) MKNK2
SCHEMBL30790389 0.62 EGFR (0.38)
SCHEMBL11880684 0.61 CHRM2 (0.30)
SCHEMBL30967258 0.61
SCHEMBL2992191 0.61
SCHEMBL31712925 0.61 SRC (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115414480-A Dianhydrogalactitol in combination with radiation for treatment of non-small cell lung cancer and glioblastoma multiforme 德玛医药 2022-12-02 CN disclosed