Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28478234 | 0.90 | ELANE (0.46) | CA1CA2ELANEMAPTTDP1 | |
| SCHEMBL4595754 | 0.83 | TDP1 (0.50) | TPMTCA1CA2ELANEMAPT | |
| SCHEMBL28514832 | 0.81 | ELANE (0.54) | ELANEMAPTTDP1POLBALDH1A1 | |
| SCHEMBL777588 | 0.81 | ELANE (0.54) | ELANEMAPTTDP1POLBALDH1A1 | |
| SCHEMBL8515413 | 0.80 | TPMT (0.48) | TPMTPTPN2PTPN1CA1CA2 | |
| SCHEMBL25968073 | 0.80 | ELANE (0.63) | CA1CA2ELANEMAPTTDP1 | |
| SCHEMBL14422832 | 0.80 | MAPT (0.62) | CA1CA2ELANEMAPT | |
| SCHEMBL811460 | 0.80 | TDP1 (0.48) | CA1CA2MAPTTDP1POLB | |
| SCHEMBL3972789 | 0.79 | ELANE (0.53) | ELANEMAPTTDP1POLBALDH1A1 | |
| SCHEMBL3788226 | 0.79 | ELANE (0.53) | ELANEMAPTTDP1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111741747-A | Porous embolic microspheres comprising a drug | 范·里恩·贝希尔有限公司 | 2020-10-02 | — | — | CN | disclosed |