SCHEMBL3972789

SCHEMBL3972789

C=C(C)C(=O)OC(=O)c1ccccc1.[Zn]

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.53
TSHR P16473 4/20 0.50
LMNA P02545 3/20 0.48
F2 P00734 1/20 0.48
ALDH1A1 P00352 4/20 0.43
TDP1 Q9NUW8 4/20 0.43
HSD17B10 Q99714 1/20 0.43
MAPT P10636 4/20 0.42
CES2 O00748 1/20 0.42
CES1 P23141 1/20 0.42
TP53 P04637 1/20 0.41
KMT2A Q03164 3/20 0.40
ATM Q13315 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
MAPK1 P28482 1/20 0.40
HIF1A Q16665 1/20 0.40
POLB P06746 1/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A3 Q01959 1/20 0.40
XBP1 P17861 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL777588 0.98 ELANE (0.54) ELANETSHRLMNAF2ALDH1A1
SCHEMBL28514832 0.98 ELANE (0.54) ELANETSHRLMNAF2ALDH1A1
SCHEMBL27711832 0.96 ELANE (0.53) ELANETSHRLMNAF2ALDH1A1
SCHEMBL3788226 0.96 ELANE (0.53) ELANETSHRLMNAF2ALDH1A1
SCHEMBL3794632 0.96 ELANE (0.53) ELANETSHRLMNAF2ALDH1A1
Benzoic Acid SCHEMBL27830619 0.95 ELANE (0.49) ELANETSHRLMNAF2ALDH1A1
SCHEMBL28478234 0.88 ELANE (0.46) ELANETSHRLMNAALDH1A1TDP1
SCHEMBL4595754 0.85 TDP1 (0.50) ELANETSHRALDH1A1TDP1HSD17B10
Methacrylic Acid SCHEMBL777587 0.84 TSHR (0.54) ELANETSHRLMNAF2ALDH1A1
SCHEMBL9772049 0.83 LMNA (0.63) ELANETSHRLMNAF2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1695956-B1 CYCLIC CARBOXYLIC ACID COMPOUND AND USE THEREOF CHUGOKU MARINE PAINTS (JP) 2012-06-20 EP disclosed
US-7557148-B2 Cyclic carboxylic acid compound and use thereof CHUGOKU MARINE PAINTS, LTD. (JP) 2009-07-07 US disclosed
US-20070105976-A1 Cyclic carboxylic acid compound and use thereof CHUGOKU MARINE PLANTS, LTD. (JP) 2007-05-10 US disclosed
CN-1886360-A Novel cycloalkenycarboxylic acid and its uses CHUGOKU MARINE PAINTS (JP) 2006-12-27 CN disclosed
CN-1159965-C Coated bis (2-pyridinetiol 1-oxide) copper salt ��ʽ����API 2004-08-04 CN disclosed
US-6630079-B2 Bis(2- pyridinethiol-1-oxide) copper salt, does not exert any adverse influence on the storage stability or antifouling effect, and the effect of the salt does not change by the coating with an acrylic resin API CORPORATION (JP) 2003-10-07 US disclosed
EP-1080640-B1 COATED BIS(2-PYRIDINETHIOL-1-OXIDE)COPPER SALT API CORP (JP) 2003-09-10 EP disclosed
US-20030124085-A1 Coated bis (2-pyridinethiol-1-oxide) copper salt API CORPORATION (JP) 2003-07-03 US disclosed
US-6544440-B1 Antifouling active ingredient for a coating for the bottom of a ship, which is safe during handling; rosin coated; biocides API CORPORATION (JP) 2003-04-08 US disclosed
EP-1227111-A1 TRIPHENYLBORON-CONTAINING POLYMERS AND USE THEREOF Yoshitomi Fine Chemicals, Ltd. (JP) 2002-07-31 EP disclosed
CN-1296380-A Coated bis (2-pyridinetiol 1-oxide) copper salt YOSHITOMI FINE CHEMICALS LTD (JP) 2001-05-23 CN disclosed
EP-1080640-A1 COATED BIS(2-PYRIDINETHIOL 1-OXIDE) COPPER SALT Yoshitomi Fine Chemicals, Ltd. (JP) 2001-03-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070105976-A1 Cyclic carboxylic acid compound and use thereof PORCN, PHOSPHO1, CA1 ELANE 2013/4885TSHR 4551/4885LMNA 4390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.