SCHEMBL4595754

SCHEMBL4595754

C=C(C)C(=O)OC(=O)c1ccc(C(=O)O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.50
POLB P06746 2/20 0.50
APEX1 P27695 1/20 0.50
HTT P42858 1/20 0.50
TSHR P16473 2/20 0.46
TP53 P04637 1/20 0.46
ELANE P08246 1/20 0.45
ALDH1A1 P00352 3/20 0.44
CA1 P00915 3/20 0.44
CA2 P00918 3/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
HSD17B10 Q99714 1/20 0.42
SRD5A2 P31213 2/20 0.41
MAPT P10636 2/20 0.41
KMT2A Q03164 1/20 0.40
CA12 O43570 1/20 0.40
CA3 P07451 1/20 0.40
TYR P14679 1/20 0.40
DRD1 P21728 1/20 0.40
CA4 P22748 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28478234 0.92 ELANE (0.46) TDP1POLBAPEX1HTTTSHR
Benzoic Acid SCHEMBL27830619 0.91 ELANE (0.49) TDP1POLBAPEX1HTTTSHR
SCHEMBL28514832 0.86 ELANE (0.54) TDP1POLBTSHRTP53ELANE
SCHEMBL777588 0.86 ELANE (0.54) TDP1POLBTSHRTP53ELANE
Terephthalic Acid SCHEMBL9766836 0.86 POLB (0.51) TDP1POLBAPEX1HTTTSHR
SCHEMBL3972789 0.85 ELANE (0.53) TDP1POLBTSHRTP53ELANE
SCHEMBL3788226 0.85 ELANE (0.53) TDP1POLBTSHRTP53ELANE
SCHEMBL3794632 0.85 ELANE (0.53) TDP1POLBTSHRTP53ELANE
SCHEMBL27711832 0.85 ELANE (0.53) TDP1POLBTSHRTP53ELANE
SCHEMBL6904760 0.84 TSHR (0.50) TDP1POLBAPEX1HTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104302830-B Motor vehicle component HP佩尔泽控股有限公司 2017-07-28 CN claimed
US-6699953-B2 A COPOLYMER OBTAINED BY COPOLYMERIZING MONOMERS CONTAINING 20 TO 80% BY WEIGHT OF BIS-2-METHACRYLOYLTHIOETHYL SULFIDE, 5-50% A BI OR MULTIFUNCTIONAL THIOL AND HAS A REFRACTIVE INDEX OF 1.58 OR MORE, AND AN ABBE'S NUMBER OF 35 OR MORE SEED CO., LTD. (JP) 2004-03-02 US claimed
US-20030130461-A1 Lens made f synthetic resin and process for producing the same SEED CO., LTD. (JP) 2003-07-10 US claimed
EP-1316820-A1 LENS MADE OF SYNTHETIC RESIN AND PROCESS FOR PRODUCING THE SAME Seed Co., Ltd. (JP) 2003-06-04 EP claimed
CN-1257063-A Producing hydroxyalkyl ester monomer by pressurized oxyethylation in desified gas ETWA TECH AG (CH) 2000-06-21 CN claimed
CN-1230154-A Removable sealing closure with closure attachment means RADLEY VALLEY PTY LTD (AU) 1999-09-29 CN claimed
EP-1316820-B1 LENS MADE OF SYNTHETIC RESIN AND PROCESS FOR PRODUCING THE SAME SEED CO LTD (JP) 2008-01-16 EP disclosed
CN-1309755-C Chromatophilous polyester copolymer prepared by terephthalic acid process, fiber using the polyester copolymer and preparation method thereof HYOSUNG CORP (KR) 2007-04-11 CN disclosed
CN-1572814-A Chromatophilous polyester copolymer prepared by terephthalic acid process, fiber using the polyester copolymer and preparation method thereof HYOSUNG CORP (KR) 2005-02-02 CN disclosed
US-6699953-B2 A COPOLYMER OBTAINED BY COPOLYMERIZING MONOMERS CONTAINING 20 TO 80% BY WEIGHT OF BIS-2-METHACRYLOYLTHIOETHYL SULFIDE, 5-50% A BI OR MULTIFUNCTIONAL THIOL AND HAS A REFRACTIVE INDEX OF 1.58 OR MORE, AND AN ABBE'S NUMBER OF 35 OR MORE SEED CO., LTD. (JP) 2004-03-02 US disclosed
US-20030130461-A1 Lens made f synthetic resin and process for producing the same SEED CO., LTD. (JP) 2003-07-10 US disclosed
EP-1316820-A1 LENS MADE OF SYNTHETIC RESIN AND PROCESS FOR PRODUCING THE SAME Seed Co., Ltd. (JP) 2003-06-04 EP disclosed
CN-1230154-A Removable sealing closure with closure attachment means RADLEY VALLEY PTY LTD (AU) 1999-09-29 CN disclosed
US-4668569-A SYNTHETIC PAPER UNITIKA LTD. (JP) 1987-05-26 US disclosed