Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 17/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 14/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20784338 | 0.82 | ADORA2A (0.74) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL20784296 | 0.80 | ADORA2B (0.56) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL20784693 | 0.78 | ADORA2B (0.63) | ADORA2AADORA2B | |
| SCHEMBL3661138 | 0.78 | ADORA2A (0.43) | ADORA2AADORA2BADORA1 | |
| SCHEMBL16505979 | 0.77 | CDK9 (0.48) | ADORA2AADORA2BADORA1 | |
| SCHEMBL24261174 | 0.77 | ADORA2A (0.66) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL20784326 | 0.77 | ADORA2A (0.54) | ADORA2AADORA2B | |
| SCHEMBL20784717 | 0.76 | ADORA2A (0.78) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL20785049 | 0.76 | ADORA2B (0.41) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL20784725 | 0.75 | ADORA2B (0.77) | ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111629728-A | Compounds and methods for modulating adenosine A2B receptor and adenosine A2A receptor | 科尔沃斯制药股份有限公司 | 2020-09-04 | — | — | CN | disclosed |