Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.36 |
| ▸ | CFD | P00746 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28953508 | 1.00 | KDM4E (0.38) | KDM4EGLASLC6A4PTGER1CFD | |
| SCHEMBL28953472 | 0.87 | SLC6A4 (0.34) | SLC6A4PTGDR2DGAT1 | |
| SCHEMBL28900742 | 0.85 | GAA (0.40) | KDM4ETDP1ALDH1A1 | |
| SCHEMBL5236256 | 0.82 | KDM4E (0.44) | KDM4EGLAPTGER1CFDMYC | |
| SCHEMBL28953476 | 0.80 | TSHR (0.38) | PTGER1 | |
| SCHEMBL20107872 | 0.79 | ALDH1A1 (0.41) | KDM4EGLACFDMYCNR4A1 | |
| SCHEMBL29816552 | 0.79 | ALDH1A1 (0.41) | KDM4EGLACFDMYCNR4A1 | |
| SCHEMBL28953507 | 0.78 | DHODH (0.42) | — | |
| SCHEMBL20242123 | 0.75 | ALDH1A1 (0.54) | KDM4EGLACFDMYCNR4A1 | |
| SCHEMBL28953505 | 0.74 | GPR17 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427109-A | Heterocyclic compounds as dihydroorotate dehydrogenase inhibitors | 詹森生物科技公司 | 2022-12-02 | — | — | CN | disclosed |