Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CFD | P00746 | 2/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20107872 | 1.00 | ALDH1A1 (0.41) | ALDH1A1KDM4EGLACFDMYC | |
| SCHEMBL29816317 | 0.87 | MEN1 (0.35) | HPGDL3MBTL1 | |
| SCHEMBL20107853 | 0.87 | MEN1 (0.35) | HPGDL3MBTL1 | |
| SCHEMBL20242123 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KDM4EGLACFDMYC | |
| SCHEMBL5236256 | 0.84 | KDM4E (0.44) | ALDH1A1KDM4EGLACFDMYC | |
| Ethane SCHEMBL6917971 | 0.83 | ALDH1A1 (0.53) | ALDH1A1KDM4EGLACFDMYC | |
| SCHEMBL20107592 | 0.81 | RORC (0.42) | ALDH1A1KDM4EGLACFDMYC | |
| SCHEMBL21853435 | 0.81 | RORC (0.42) | ALDH1A1KDM4EGLACFDMYC | |
| SCHEMBL29512881 | 0.81 | RORC (0.42) | ALDH1A1KDM4EGLACFDMYC | |
| SCHEMBL28900699 | 0.79 | KDM4E (0.38) | ALDH1A1KDM4EGLACFDMYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115557907-B | 2,4, 5-Trisubstituted 1,2, 4-triazolones as DHODH inhibitors | 拜耳股份有限公司 | 2024-12-06 | — | — | CN | disclosed |
| CN-115557907-A | 2,4, 5-trisubstituted 1,2, 4-triazolones as DHODH inhibitors | 拜耳股份有限公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-110023302-B | 2,4, 5-trisubstituted 1,2, 4-triazolones as DHODH inhibitors | 拜耳股份有限公司 | 2022-07-26 | — | — | CN | disclosed |