Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 9/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | GMNN | O75496 | 1/20 | 0.65 |
| ▸ | TTR | P02766 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.65 |
| ▸ | DHODH | Q02127 | 1/20 | 0.65 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28689427 | 0.88 | LMNA (0.72) | LMNAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL28678451 | 0.87 | MEN1 (0.72) | LMNAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL12608890 | 0.83 | LMNA (0.79) | LMNAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL5836241 | 0.81 | LMNA (0.65) | LMNAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL5953848 | 0.81 | LMNA (0.78) | LMNAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL6105933 | 0.81 | LMNA (0.56) | LMNAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL4767625 | 0.80 | KMT2A (0.64) | LMNAPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL18689435 | 0.80 | LMNA (0.60) | LMNAPOLBMEN1KMT2AALDH1A1 | |
| Niflumic Acid SCHEMBL29364001 | 0.80 | DHODH (1.00) | LMNAPOLBMEN1KMT2AALDH1A1 | |
| Niflumic Acid SCHEMBL24706 | 0.80 | DHODH (1.00) | LMNAPOLBMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909053-B | Diarylamine unit-based amide derivative and preparation method and application thereof | 湖北省生物农药工程研究中心 | 2022-12-06 | — | — | CN | disclosed |
| CN-111909053-A | Diarylamine unit-based amide derivative and preparation method and application thereof | 湖北省生物农药工程研究中心 | 2020-11-10 | — | — | CN | disclosed |