Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4610295 | 0.79 | GAA (0.40) | PLAUELANEF2KLKB1SIRT5 | |
| SCHEMBL27564845 | 0.77 | TSHR (0.44) | F2LMNAMAPTRAB9AKDM4E | |
| SCHEMBL28710658 | 0.76 | GRN (0.35) | LMNAMAPTGAAKDM4E | |
| SCHEMBL27872779 | 0.76 | CYP4F2 (0.32) | KDM4EALDH1A1 | |
| SCHEMBL27934670 | 0.74 | NPC1 (0.38) | LMNAMAPTRAB9AKDM4ENPC1 | |
| SCHEMBL6633229 | 0.73 | SMN1; SMN2 (0.42) | PLAUELANEGAARAB9AALDH1A1 | |
| SCHEMBL12986494 | 0.73 | NPC1 (0.39) | GAARAB9AALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL5650020 | 0.72 | SMN1; SMN2 (0.41) | LMNARAB9AKDM4EALDH1A1KMT2A | |
| SCHEMBL2891010 | 0.72 | CYP4F2 (0.33) | — | |
| SCHEMBL6864005 | 0.71 | NOS1 (0.36) | PLAUELANEF2KLKB1SIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117693502-A | Compounds for inhibiting or degrading ITK, compositions comprising the same, methods of making the same, and methods of using the same | 纽力克斯治疗公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-107250133-B | Hydroxyalkyl piperazine derivatives as CXCR3 receptor modulators | 爱杜西亚药品有限公司 | 2020-09-15 | — | — | CN | disclosed |