Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.42 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.42 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 3/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6634859 | 0.83 | RAB9A (0.41) | SMN1; SMN2GAAALDH1A1HTTTSHR | |
| SCHEMBL6631787 | 0.82 | KMT2A (0.42) | SMN1; SMN2GAAALDH1A1HTTTSHR | |
| SCHEMBL4610295 | 0.79 | GAA (0.40) | SMN1; SMN2GAAALDH1A1NPC1PLAU | |
| SCHEMBL6629379 | 0.76 | NPC1 (0.46) | SMN1; SMN2NPC1PLAUELANERAB9A | |
| SCHEMBL6632002 | 0.76 | SMN1; SMN2 (0.53) | SMN1; SMN2GAAALDH1A1HTTNPC1 | |
| SCHEMBL6630652 | 0.75 | GAA (0.45) | SMN1; SMN2GAAALDH1A1HTTNPC1 | |
| SCHEMBL27406517 | 0.74 | SMN1; SMN2 (0.42) | SMN1; SMN2GAAALDH1A1HTTTSHR | |
| SCHEMBL28901178 | 0.73 | PLAU (0.38) | SMN1; SMN2GAAALDH1A1HTTNPC1 | |
| SCHEMBL27874680 | 0.72 | SMN1; SMN2 (0.48) | SMN1; SMN2GAAALDH1A1HTTTSHR | |
| SCHEMBL6635974 | 0.72 | MAPT (0.43) | SMN1; SMN2GAAALDH1A1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458375-A2 | COMPOSITIONS FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003051842-A2 | COMPOSITIONS DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2003-06-26 | — | — | WO | disclosed |