SCHEMBL28901302

SCHEMBL28901302

O=C1CCc2ccc(-c3ccc4ccccc4c3)cc2N1CCN1CCCCC1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 2/20 0.45
DRD4 P21917 2/20 0.45
DRD3 P35462 2/20 0.45
BRD4 O60885 1/20 0.43
GRIN1 Q05586 1/20 0.43
GRIN2B Q13224 1/20 0.43
CHRM2 P08172 1/20 0.43
CHRM4 P08173 1/20 0.43
CHRM5 P08912 1/20 0.43
CHRM1 P11229 1/20 0.43
CHRM3 P20309 1/20 0.43
NOS3 P29474 1/20 0.43
NOS1 P29475 1/20 0.43
MCHR1 Q99705 1/20 0.42
HRH3 Q9Y5N1 1/20 0.42
TRPV1 Q8NER1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29924461 1.00 DRD2 (0.45) DRD2DRD4DRD3BRD4GRIN1
SCHEMBL28901280 0.97 DRD2 (0.43) DRD2DRD4DRD3BRD4GRIN1
SCHEMBL29924295 0.97 DRD2 (0.43) DRD2DRD4DRD3BRD4GRIN1
SCHEMBL28901307 0.90 DRD2 (0.47) DRD2DRD4DRD3BRD4CHRM2
SCHEMBL29924394 0.90 DRD2 (0.47) DRD2DRD4DRD3BRD4CHRM2
SCHEMBL28901301 0.84 DRD2 (0.51) DRD2DRD4DRD3CHRM2CHRM4
SCHEMBL29924513 0.84 DRD2 (0.51) DRD2DRD4DRD3CHRM2CHRM4
SCHEMBL29924398 0.82 ADRA1B (0.47) DRD2DRD4DRD3BRD4GRIN1
SCHEMBL28901351 0.82 ADRA1B (0.47) DRD2DRD4DRD3BRD4GRIN1
SCHEMBL31033189 0.80 DRD2 (0.64) DRD2DRD4DRD3GRIN1GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115073370-A Novel alkylammonium compound or salt, isomer, preparation method and application thereof 成都硕德药业有限公司 2022-09-20 CN disclosed