Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | CTSD | P07339 | 4/20 | 0.59 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.57 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.57 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29924236 | 1.00 | KMT2A (0.77) | KMT2AALDH1A1MAPTHPGDCYP3A4 | |
| SCHEMBL28901354 | 1.00 | KMT2A (0.77) | KMT2AALDH1A1MAPTHPGDCYP3A4 | |
| SCHEMBL29924325 | 1.00 | KMT2A (0.77) | KMT2AALDH1A1MAPTHPGDCYP3A4 | |
| SCHEMBL22502244 | 0.90 | KMT2A (0.64) | KMT2AALDH1A1MAPTHPGDCYP3A4 | |
| SCHEMBL22502246 | 0.90 | KMT2A (0.64) | KMT2AALDH1A1MAPTHPGDCYP3A4 | |
| SCHEMBL29378940 | 0.90 | KMT2A (0.64) | KMT2AALDH1A1MAPTHPGDCYP3A4 | |
| SCHEMBL8318576 | 0.89 | KMT2A (0.62) | KMT2AALDH1A1MAPTHPGDCYP3A4 | |
| SCHEMBL29115514 | 0.85 | KMT2A (0.58) | KMT2AALDH1A1HPGDCTSDNPC1 | |
| SCHEMBL8259636 | 0.83 | KMT2A (0.62) | KMT2AALDH1A1MAPTCYP3A4CYP2D6 | |
| SCHEMBL149313 | 0.83 | ALDH1A1 (0.56) | KMT2AALDH1A1HPGDCTSDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115073373-A | Method for asymmetric synthesis of (R) -5' -methoxy labdanin | 广东嘉博制药有限公司 | 2022-09-20 | — | — | CN | disclosed |