Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | C5 | P01031 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CTSD | P07339 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22502244 | 1.00 | KMT2A (0.64) | KMT2AC5NPSR1PTGDR2ALDH1A1 | |
| SCHEMBL22502246 | 1.00 | KMT2A (0.64) | KMT2AC5NPSR1PTGDR2ALDH1A1 | |
| SCHEMBL29924325 | 0.90 | KMT2A (0.77) | KMT2APTGDR2ALDH1A1MAPTHPGD | |
| SCHEMBL28901354 | 0.90 | KMT2A (0.77) | KMT2APTGDR2ALDH1A1MAPTHPGD | |
| SCHEMBL28901353 | 0.90 | KMT2A (0.77) | KMT2APTGDR2ALDH1A1MAPTHPGD | |
| SCHEMBL29924236 | 0.90 | KMT2A (0.77) | KMT2APTGDR2ALDH1A1MAPTHPGD | |
| SCHEMBL29115514 | 0.81 | KMT2A (0.58) | KMT2AALDH1A1HPGDCTSD | |
| SCHEMBL8318576 | 0.80 | KMT2A (0.62) | KMT2AALDH1A1MAPTHPGDCYP3A4 | |
| SCHEMBL8892152 | 0.78 | ALDH1A1 (0.44) | KMT2AC5PTGDR2ALDH1A1MAPT | |
| SCHEMBL8894347 | 0.75 | KMT2A (0.54) | KMT2APTGDR2ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3947352-A1 | COMPLEMENT MODULATORS AND RELATED METHODS | RA Pharmaceuticals, Inc. (US) | 2022-02-09 | — | — | EP | disclosed |