Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23249884 | 0.90 | HPGD (0.53) | HPGDRECQLEPHX1KDM4EMAPT | |
| SCHEMBL23783193 | 0.89 | HPGD (0.43) | HPGDRECQLEPHX1KDM4EMAPT | |
| SCHEMBL26665781 | 0.83 | HPGD (0.49) | HPGDRECQLEPHX1KDM4EMAPT | |
| SCHEMBL34461286 | 0.83 | RECQL (0.48) | HPGDRECQLEPHX1KDM4EMAPT | |
| SCHEMBL31140989 | 0.81 | HPGD (0.47) | HPGDRECQLEPHX1KDM4EMAPT | |
| SCHEMBL26665784 | 0.81 | HPGD (0.50) | HPGDRECQLEPHX1KDM4EMAPT | |
| SCHEMBL26469848 | 0.79 | NR1H2 (0.40) | HPGDRECQLEPHX1KDM4EMAPT | |
| SCHEMBL3254458 | 0.79 | EPHX1 (0.54) | HPGDRECQLEPHX1KDM4EMAPT | |
| SCHEMBL23797805 | 0.79 | FAAH (0.44) | HPGDRECQLEPHX1KDM4EMAPT | |
| SCHEMBL118561 | 0.77 | GPR119 (0.57) | HPGDRECQLEPHX1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279370-A | Compounds for targeted degradation of BRD9 | C4医药公司 | 2022-11-01 | — | — | CN | disclosed |