Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.64 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 2/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PDE9A | O76083 | 1/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19002274 | 0.86 | POLB (0.50) | POLBACMSDALDH1A1KDM4EHPGD | |
| SCHEMBL28477518 | 0.83 | ACMSD (0.64) | POLBACMSDALDH1A1KDM4EHPGD | |
| SCHEMBL30050428 | 0.83 | ACMSD (0.64) | POLBACMSDALDH1A1KDM4EHPGD | |
| SCHEMBL29731504 | 0.83 | ACMSD (0.64) | POLBACMSDSIRT1ALDH1A1KDM4E | |
| SCHEMBL28843348 | 0.83 | ACMSD (0.67) | POLBACMSDSIRT1KDM4EGAA | |
| SCHEMBL28483299 | 0.83 | ACMSD (0.64) | POLBACMSDALDH1A1KDM4EHPGD | |
| SCHEMBL30051338 | 0.83 | ACMSD (0.64) | POLBACMSDALDH1A1KDM4EHPGD | |
| SCHEMBL29731230 | 0.83 | ACMSD (0.67) | POLBACMSDSIRT1KDM4EGAA | |
| SCHEMBL28481873 | 0.83 | ACMSD (0.64) | POLBACMSDSIRT1ALDH1A1KDM4E | |
| SCHEMBL5937494 | 0.83 | ACMSD (0.61) | POLBACMSDALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111961039-B | Myricetin derivative containing substituted pyrimidine, preparation method and application thereof | 贵州大学 | 2022-11-08 | — | — | CN | disclosed |
| CN-111961039-A | Myricetin derivative containing substituted pyrimidine, preparation method and application thereof | 贵州大学 | 2020-11-20 | — | — | CN | disclosed |