Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 13/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 13/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 12/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 12/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 12/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 11/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 10/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | GABRE | P78334 | 1/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1019178 | 0.81 | GABRG2 (0.46) | GABRG2GABRB3GABRA1GABRA2GABRA5 | |
| SCHEMBL29208228 | 0.80 | GABRG2 (0.44) | GABRG2GABRB3GABRA1GABRA2GABRA5 | |
| SCHEMBL29700722 | 0.80 | GABRG2 (0.44) | GABRG2GABRB3GABRA1GABRA2GABRA5 | |
| SCHEMBL988761 | 0.80 | POLB (0.54) | GABRG2GABRB3GABRA1GABRA2GABRA5 | |
| SCHEMBL2134366 | 0.79 | MAPK1 (0.52) | GABRG2GABRB3GABRA1GABRA2GABRA5 | |
| SCHEMBL30271936 | 0.79 | MAPK1 (0.52) | GABRG2GABRB3GABRA1GABRA2GABRA5 | |
| SCHEMBL31515460 | 0.79 | SIRT6 (0.52) | GABRG2GABRB3GABRA1GABRA2GABRA5 | |
| SCHEMBL2645097 | 0.79 | GABRG2 (0.48) | GABRG2GABRB3GABRA1GABRA2GABRA5 | |
| SCHEMBL2646157 | 0.79 | SIRT6 (0.52) | GABRG2GABRB3GABRA1GABRA2GABRA5 | |
| SCHEMBL2645705 | 0.79 | GABRG2 (0.47) | GABRG2GABRB3GABRA1GABRA2GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115087658-A | Sulfonamide or sulfenamide compounds having BRD 4-inducing proteolytic activity, and pharmaceutical use thereof | 田边三菱制药株式会社 | 2022-09-20 | — | — | CN | disclosed |