Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.63 |
| ▸ | HPGD | P15428 | 5/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28902197 | 0.87 | MAOB (0.57) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL28902171 | 0.81 | MAOA (0.55) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL30167104 | 0.78 | HSD17B3 (0.63) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL28902168 | 0.78 | HSD17B3 (0.63) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL28902189 | 0.76 | MAOA (0.49) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL28902185 | 0.75 | PPARG (0.59) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL30787479 | 0.75 | MAOB (0.60) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL28960196 | 0.74 | KDM4E (0.54) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL28902175 | 0.74 | KDM4E (0.57) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL28902174 | 0.73 | KDM4E (0.60) | ALDH1A1KDM4EHPGDHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115246805-B | Chromone-aniline alpha-glucosidase inhibitor and preparation method and application thereof | 贵州医科大学 | 2024-01-19 | — | — | CN | disclosed |
| CN-115246805-A | Chromone-aniline alpha-glucosidase inhibitor and preparation method and application thereof | 贵州医科大学 | 2022-10-28 | — | — | CN | disclosed |