Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | BLM | P54132 | 2/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | MPO | P05164 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.57 |
| ▸ | PTPRA | P18433 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28902203 | 1.00 | KDM4E (0.59) | KDM4EKMT2AMAPTLMNATSHR | |
| SCHEMBL31036029 | 0.89 | KMT2A (0.66) | KDM4EKMT2AMAPTLMNATSHR | |
| SCHEMBL503548 | 0.89 | KMT2A (0.66) | KDM4EKMT2AMAPTLMNATSHR | |
| SCHEMBL29809822 | 0.89 | KMT2A (0.66) | KDM4EKMT2AMAPTLMNATSHR | |
| SCHEMBL8769008 | 0.89 | KMT2A (0.66) | KDM4EKMT2AMAPTLMNATSHR | |
| SCHEMBL2033277 | 0.89 | SOS2 (0.68) | KDM4EKMT2AMAPTLMNATSHR | |
| SCHEMBL31369774 | 0.89 | SOS2 (0.68) | KDM4EKMT2AMAPTLMNATSHR | |
| SCHEMBL10023253 | 0.89 | SOS2 (0.68) | KDM4EKMT2AMAPTLMNATSHR | |
| SCHEMBL2033276 | 0.89 | SOS2 (0.68) | KDM4EKMT2AMAPTLMNATSHR | |
| SCHEMBL29405720 | 0.89 | SOS2 (0.68) | KDM4EKMT2AMAPTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936157-A | Fibroblast growth factor analogs and uses thereof | 佛罗里达大学研究基金会 | 2020-11-13 | — | — | CN | disclosed |