SCHEMBL2033276

SCHEMBL2033276

Cc1cccc2c(C[C@H](N)C(=O)O)c[nH]c12

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SOS2 Q07890 1/20 0.68
MAPT P10636 6/20 0.62
KMT2A Q03164 3/20 0.62
KDM4E B2RXH2 3/20 0.62
LMNA P02545 2/20 0.62
TSHR P16473 2/20 0.62
BLM P54132 2/20 0.62
PMP22 Q01453 2/20 0.62
MEN1 O00255 2/20 0.62
MPO P05164 1/20 0.62
HIF1A Q16665 1/20 0.62
TNF P01375 1/20 0.57
HTR2A P28223 2/20 0.55
NPSR1 Q6W5P4 2/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
ALDH1A1 P00352 2/20 0.51
CYP3A4 P08684 1/20 0.51
HTR1A P08908 1/20 0.51
ADORA3 P0DMS8 1/20 0.51
ALOX15 P16050 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31369774 1.00 SOS2 (0.68) SOS2MAPTKMT2AKDM4ELMNA
SCHEMBL2033277 1.00 SOS2 (0.68) SOS2MAPTKMT2AKDM4ELMNA
SCHEMBL29405720 1.00 SOS2 (0.68) SOS2MAPTKMT2AKDM4ELMNA
SCHEMBL10023253 1.00 SOS2 (0.68) SOS2MAPTKMT2AKDM4ELMNA
SCHEMBL10068458 0.89 SOS2 (0.68) SOS2MAPTKMT2AKDM4ELMNA
SCHEMBL28902203 0.89 KDM4E (0.59) SOS2MAPTKMT2AKDM4ELMNA
SCHEMBL28902202 0.89 KDM4E (0.59) SOS2MAPTKMT2AKDM4ELMNA
SCHEMBL21644779 0.86 MAPT (0.62) SOS2MAPTKMT2AKDM4ELMNA
SCHEMBL21644780 0.86 MAPT (0.62) SOS2MAPTKMT2AKDM4ELMNA
SCHEMBL29379020 0.86 MAPT (0.62) SOS2MAPTKMT2AKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 477 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144842-A1 PHARMACEUTICAL COMPOSITION COMPRISING TRYPTOPHAN AND PHYLLOKININ DERIVATIVE FOR USE IN TREATING PSYCHIATRIC AND PSYCHOLOGICAL CONDITIONS TEMPLE OTORONGO LLC (US) 2026-05-28 US claimed
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 US claimed
US-12351573-B2 Compounds for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2025-07-08 US claimed
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 US claimed
CN-118406439-B Chemical mechanical polishing composition and application thereof in tungsten chemical mechanical polishing 万华化学集团电子材料有限公司 2024-10-18 CN claimed
CN-118406439-A Chemical mechanical polishing composition and application thereof in tungsten chemical mechanical polishing 万华化学集团电子材料有限公司 2024-07-30 CN claimed
CN-118184756-A Engineered Leptospira perfoliatum lectin mutant and application thereof 浙江大学医学院附属第一医院(浙江省第一医院) 2024-06-14 CN claimed
CN-114940979-B Method for improving cation-pi interaction by utilizing genetic code expansion and application 杭州嵌化合生医药科技有限公司 2024-01-23 CN claimed
US-11845808-B2 Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases JANSSEN BIOTECH, INC. (US) 2023-12-19 US claimed
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2023-04-13 US claimed
US-20080028488-A1 USE OF TRYPTOPHAN INDOLE AND ANTHRANILATE ANALOGS AS PLANT TRANSFORMATION SELECTION AGENTS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2008-01-31 US claimed
US-20070293656-A1 COLLAGEN BINDING PEPTIDES EPIX PHARMACEUTICALS, INC. 2007-12-20 US claimed
WO-2007084264-A2 METHODS FOR MYOCARDIAL IMAGING EPIX PHARMACEUTICALS, INC. (US) 2007-07-26 WO claimed
EP-1101823-A2 Process for the preparation of indigo derivatives and dyes for ceratinous fibers containing the same Wella Aktiengesellschaft (DE) 2001-05-23 EP claimed
EP-1029073-A1 METHOD AND AGENT FOR DETERMINING AN ENZYMATIC ACTIVITY SUCH AS DEAMINASE BIO MERIEUX (FR) 2000-08-23 EP claimed
WO-1999024604-A1 METHOD AND AGENT FOR DETERMINING AN ENZYMATIC ACTIVITY SUCH AS DEAMINASE BIO MERIEUX (FR) 1999-05-20 WO claimed
US-5034318-A Culturing Coryneform glutamic acid producing bacteria with plasmids AJINOMOTO CO., INC. (JP) 1991-07-23 US claimed
EP-0192948-A1 Cholecystokinin antagonist compounds, process for their preparation and pharmaceutical compositions containing them MERCK & CO. INC. (US) 1986-09-03 EP claimed
US-3963572-A Fermentative process for the production of L-tryptophan and its derivatives AB BOFORS (SW) 1976-06-15 US claimed
US-3930948-A ENZYMATIC METHOD FOR PRODUCING AROMATIC ETHYLAMINES AJINOMOTO CO., INC. (JA) 1976-01-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12351573-B2 Compounds for use in synthesis of peptidomimetics DNPEP, NPEPPS, PAM SOS2 2068/4885MAPT 1350/4885KMT2A 1848/4885
US-20260144842-A1 PHARMACEUTICAL COMPOSITION COMPRISING TRYPTOPHAN AND PHYLLOKININ DERIVATIVE FOR USE IN TREATING PSYCHIATRIC AND PSYCHOLOGICAL CONDITIONS OPRK1, TPH1, HTR3C SOS2 4035/4885MAPT 1093/4885KMT2A 4104/4885
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF TST, ABAT, AADAC SOS2 4848/4885MAPT 1493/4885KMT2A 1523/4885
US-20070293656-A1 COLLAGEN BINDING PEPTIDES COL14A1, COL2A1, COL1A1 SOS2 3918/4885MAPT 1814/4885KMT2A 4714/4885
US-11845808-B2 Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases IL23R, IL1RN, VIP SOS2 3562/4885MAPT 2759/4885KMT2A 4527/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT SOS2 4567/4885MAPT 1679/4885KMT2A 2188/4885
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES BCAT1, BCAT2, PELP1 SOS2 4316/4885MAPT 1809/4885KMT2A 3415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.