Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.46 |
| ▸ | RXRA | P19793 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | C5 | P01031 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28902296 | 1.00 | PPARG (0.46) | PPARGRXRAMAPTKMT2AKDM4E | |
| SCHEMBL17819189 | 0.93 | PPARG (0.48) | PPARGRXRAMAPTKDM4EALDH1A1 | |
| SCHEMBL17819186 | 0.93 | PPARG (0.48) | PPARGRXRAMAPTKDM4EALDH1A1 | |
| SCHEMBL23036665 | 0.91 | PPARG (0.44) | PPARGRXRAMAPTKMT2AKDM4E | |
| SCHEMBL23036311 | 0.91 | PPARG (0.44) | PPARGRXRAMAPTKMT2AKDM4E | |
| SCHEMBL24740963 | 0.87 | LMNA (0.51) | PPARGRXRAMAPTKMT2AKDM4E | |
| SCHEMBL23036686 | 0.87 | PPARG (0.43) | PPARGRXRAMAPTKMT2AKDM4E | |
| SCHEMBL23036683 | 0.87 | PPARG (0.43) | PPARGRXRAMAPTKMT2AKDM4E | |
| SCHEMBL23036517 | 0.86 | ALDH1A1 (0.41) | MAPTKMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL23036515 | 0.86 | ALDH1A1 (0.41) | MAPTKMT2AKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112020354-A | Anti-cancer indenes, indanes, aza-indenes, aza-indanes, pharmaceutical compositions and uses | ADT制药有限责任公司 | 2020-12-01 | — | — | CN | claimed |