Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 4/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 2/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.30 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.30 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.30 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.30 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.30 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.30 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28903853 | 0.87 | AAK1 (0.45) | SMPD3CSNK2A1CSNK2A2AAK1DYRK1A | |
| SCHEMBL23931661 | 0.82 | SMPD3 (0.35) | SMPD3CSNK2A1CSNK2A2APOBEC3AAPOBEC3G | |
| SCHEMBL23931659 | 0.82 | SMPD3 (0.38) | SMPD3CSNK2A1CSNK2A2APOBEC3AAPOBEC3G | |
| SCHEMBL23931621 | 0.79 | SMPD3 (0.39) | SMPD3CSNK2A1CSNK2A2APOBEC3AAPOBEC3G | |
| SCHEMBL23931622 | 0.78 | SMPD3 (0.37) | SMPD3CSNK2A1CSNK2A2APOBEC3AAPOBEC3G | |
| SCHEMBL29660252 | 0.78 | AAK1 (0.42) | SMPD3CSNK2A1CSNK2A2APOBEC3AAPOBEC3G | |
| SCHEMBL29660281 | 0.76 | AAK1 (0.43) | SMPD3CSNK2A1CSNK2A2APOBEC3AAPOBEC3G | |
| SCHEMBL31677677 | 0.71 | AAK1 (0.48) | SMPD3AAK1PIM1 | |
| SCHEMBL20081018 | 0.70 | AAK1 (0.50) | SMPD3AAK1 | |
| SCHEMBL29660254 | 0.68 | AAK1 (0.56) | SMPD3CSNK2A1AAK1GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427045-A | 4- (3- (pyridin-3-yl) pyrazolo [1,5-a ] pyrimidin-5-yl) piperazine for the treatment of COV-229E or COV-OC43 coronavirus infection | 莱西肯医药有限公司 | 2022-12-02 | — | — | CN | disclosed |