Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | MPO | P05164 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | TACR1 | P25103 | 2/20 | 0.61 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | HTR1D | P28221 | 1/20 | 0.54 |
| ▸ | HTR1B | P28222 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HTR1E | P28566 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL475351 | 0.95 | MAPT (0.74) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL289044 | 0.95 | MAPT (0.74) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL27645874 | 0.90 | MAPT (0.67) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL21059260 | 0.89 | MAPT (0.70) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL120931 | 0.88 | KDM4E (0.69) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL8406415 | 0.88 | MAPT (0.65) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL5065255 | 0.88 | KDM4E (0.65) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL17503190 | 0.88 | MAPT (0.72) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL1640627 | 0.88 | MAPT (0.68) | MAPTKDM4EMEN1LMNAKMT2A | |
| SCHEMBL626831 | 0.88 | MAPT (0.72) | MAPTKDM4EMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4149493-A1 | METHOD OF TREATMENT OF CANCER OR TUMOUR | Adaptimmune Limited (GB) | 2023-03-22 | — | — | EP | disclosed |
| EP-4149492-A1 | MODIFIED IPSCS | Adaptimmune Limited (GB) | 2023-03-22 | — | — | EP | disclosed |
| EP-4149631-A1 | METHOD OF TREATMENT OF CANCER OR TUMOUR | Adaptimmune Limited (GB) | 2023-03-22 | — | — | EP | disclosed |
| WO-2021229234-A1 | METHOD OF TREATMENT OF CANCER OR TUMOUR | ADAPTIMMUNE LIMITED (GB) | 2021-11-18 | — | — | WO | disclosed |
| WO-2021229235-A1 | METHOD OF TREATMENT OF CANCER OR TUMOUR | ADAPTIMMUNE LIMITED (GB) | 2021-11-18 | — | — | WO | disclosed |
| WO-2021229212-A1 | MODIFIED IPSCS | ADAPTIMMUNE LIMITED (GB) | 2021-11-18 | — | — | WO | disclosed |
| CN-106148311-B | A kind of mutant of D-Psicose -3- epimerase and its application | 上海立足生物科技有限公司 | 2019-06-21 | — | — | CN | disclosed |
| CN-107746426-A | Wild almond protein sources α Glucosidase inhibitor peptides through protease P rote AX enzymolysis and preparation method thereof | 重庆三峡学院 | 2018-03-02 | — | — | CN | disclosed |
| CN-107698659-A | Wild almond protein sources ɑ Glucosidase inhibitor peptides through protease M enzymolysis and preparation method thereof | 重庆三峡学院 | 2018-02-16 | — | — | CN | disclosed |
| CN-105622727-A | Method for synthesizing leuprorelin by solid phase and liquid phase | WUXI ASIAPEPTIDE BIOTECHNOLOGY CO LTD | 2016-06-01 | — | — | CN | disclosed |
| US-20140187482-A1 | INSULIN PREPARATION | THE DOSHISHA (JP) | 2014-07-03 | — | — | US | disclosed |
| US-20090023188-A1 | Heparin/heparosan synthase from P. multocida and methods of making and using same | NATIONAL SCIENCE FOUNDATION | 2009-01-22 | — | — | US | disclosed |
| EP-0498665-B1 | Hydroxamic acids derivatives, process for their preparation and use thereof | BRITISH BIOTECH PHARM (GB) | 1996-04-24 | — | — | EP | disclosed |