Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | MPO | P05164 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.69 |
| ▸ | TACR1 | P25103 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MC4R | P32245 | 2/20 | 0.54 |
| ▸ | MC5R | P33032 | 1/20 | 0.54 |
| ▸ | MC3R | P41968 | 1/20 | 0.54 |
| ▸ | APAF1 | O14727 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL289044 | 0.93 | MAPT (0.74) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL475351 | 0.93 | MAPT (0.74) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL1239230 | 0.92 | MEN1 (0.59) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL243575 | 0.91 | TACR1 (0.62) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL10359013 | 0.91 | TACR1 (0.62) | KDM4EMAPTMEN1KMT2ALMNA | |
| Tyrosine SCHEMBL1065122 | 0.91 | KMT2A (0.68) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL17503190 | 0.90 | MAPT (0.72) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL4261073 | 0.88 | MAPT (0.67) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL27645874 | 0.88 | MAPT (0.67) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL220264 | 0.88 | MAPT (0.67) | KDM4EMAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1002 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113514518-B | Preparation method of hydrogen peroxide sensor based on polypeptide-enzyme composite material | 江苏大学 | 2023-05-09 | — | — | CN | claimed |
| CN-115746089-A | Allyl alcohol derivatives and their use in protein modification | 国科大杭州高等研究院 | 2023-03-07 | — | — | CN | claimed |
| CN-113514518-A | Preparation method of hydrogen peroxide sensor based on polypeptide-enzyme composite material | 江苏大学 | 2021-10-19 | — | — | CN | claimed |
| CN-109156824-A | A kind of preoperative special meals drink and the preparation method and application thereof taken of diabetes patient | 广州钮和生物科技有限公司 | 2019-01-08 | — | — | CN | claimed |
| US-20130012457-A1 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING | THE UNIVERSITY OF LEEDS | 2013-01-10 | — | — | US | claimed |
| EP-2364991-A1 | A process for the preparation of poly-alfa-glutamic acid and derivatives thereof | Cell Therapeutics, Inc. - Sede Secondaria (IT) | 2011-09-14 | — | — | EP | claimed |
| EP-2027145-A1 | A PROCESS FOR THE PREPARATION OF POLY-ALFA-GLUTAMIC ACID AND DERIVATIVES THEREOF | Cell Therapeutics, Inc. - Sede Secondaria (IT) | 2009-02-25 | — | — | EP | claimed |
| WO-2007144140-A1 | A PROCESS FOR THE PREPARATION OF POLY-ALFA-GLUTAMIC ACID AND DERIVATIVES THEREOF | CELL THERAPEUTICS INC. - SEDE SECONDARIA (IT) | 2007-12-21 | — | — | WO | claimed |
| CN-117482145-A | Traditional Chinese medicine extract, preparation method thereof and application thereof in preparation of medicine for treating Alzheimer's disease | 中国科学院长春应用化学研究所 | 2024-02-02 | — | — | CN | disclosed |
| CN-113514518-B | Preparation method of hydrogen peroxide sensor based on polypeptide-enzyme composite material | 江苏大学 | 2023-05-09 | — | — | CN | disclosed |
| CN-115989033-A | Compositions and methods for TCR reprogramming using CD 70-specific fusion proteins | T细胞受体治疗公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-112175927-B | Base editing tool and application thereof | 上海科技大学 | 2023-04-18 | — | — | CN | disclosed |
| CN-114957467-B | Nanobody specifically binding TNF-alpha and application thereof | 天津大学 | 2023-04-18 | — | — | CN | disclosed |
| CN-115960232-A | anti-CTLA 4 monoclonal antibody or antigen binding fragment thereof, pharmaceutical composition and application | 中山康方生物医药有限公司 | 2023-04-14 | — | — | CN | disclosed |
| US-5741772-A | POLYPEPTIDE | AMGEN INC. (US) | 1998-04-21 | — | — | US | disclosed |
| US-5641655-A | GENETIC ENGINEERED DNA ENCODING A PROTEIN FUSION | ZYMOGENETICS, INC. (US) | 1997-06-24 | — | — | US | disclosed |
| US-5605818-A | FROM CULTURE MEDIUM CONTAINING CORYNEBACTERIUM OR BREVIBACTERIUM | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-02-25 | — | — | US | disclosed |
| WO-1996029406-A2 | NUCLEAR LOCALIZATION FACTOR ASSOCIATED WITH CIRCADIAN RHYTHMS | THE ROCKEFELLER UNIVERSITY (US) | 1996-09-26 | — | — | WO | disclosed |
| EP-0564552-A1 | USE OF CALPAIN INHIBITORS IN THE INHIBITION AND TREATMENT OF NEURODEGENERATION | CORTEX PHARMACEUTICALS, INC. (US) | 1993-10-13 | — | — | EP | disclosed |
| WO-1992011850-A2 | USE OF CALPAIN INHIBITORS IN THE INHIBITION AND TREATMENT OF NEURODEGENERATION | CORTEX PHARMACEUTICALS, INC. (US) | 1992-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012457-A1 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING | IAPP, TAGLN2, KRT18 | KDM4E 4717/4885MAPT 152/4885MEN1 1986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.