Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 15/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.68 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.64 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.61 |
| ▸ | APP | P05067 | 1/20 | 0.58 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.56 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.56 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2895511 | 0.99 | MCHR1 (0.68) | MCHR1KCNH2HRH3MAPK14APP | |
| SCHEMBL31573862 | 0.83 | MCHR1 (0.68) | MCHR1KCNH2HRH3MAPK14APP | |
| SCHEMBL2891930 | 0.83 | MCHR1 (0.58) | MCHR1KCNH2HRH3MAPK14APP | |
| SCHEMBL2891931 | 0.83 | MCHR1 (0.58) | MCHR1KCNH2HRH3MAPK14APP | |
| SCHEMBL2891115 | 0.81 | MCHR1 (0.82) | MCHR1KCNH2HRH3MAPK14 | |
| SCHEMBL1753676 | 0.81 | MCHR1 (1.00) | MCHR1KCNH2HRH3 | |
| SCHEMBL2895116 | 0.81 | MCHR1 (0.81) | MCHR1KCNH2HRH3 | |
| SCHEMBL28783630 | 0.81 | HRH3 (0.87) | MCHR1KCNH2HRH3MAPK14APP | |
| SCHEMBL1002648 | 0.80 | MCHR1 (0.53) | MCHR1KCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL30701784 | 0.80 | HRH3 (0.85) | MCHR1KCNH2HRH3MAPK14APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732456-B2 | Pyridone derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-06-08 | — | — | US | disclosed |
| US-20070208046-A1 | Pyridone derivative | MSD K.K. (JP) | 2007-09-06 | — | — | US | disclosed |
| EP-1741703-A1 | PYRIDONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208046-A1 | Pyridone derivative | CHRM1, XDH, MTR | MCHR1 535/4885KCNH2 1619/4885HRH3 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.