Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.78 |
| ▸ | TSHR | P16473 | 1/20 | 0.78 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 2/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.41 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29459723 | 0.89 | — | — | |
| SCHEMBL58273 | 0.89 | — | — | |
| O-Xylene SCHEMBL28610813 | 0.86 | ALDH1A1 (0.95) | ALDH1A1TSHRLMNAKMT2AMEN1 | |
| SCHEMBL29030634 | 0.86 | ALDH1A1 (0.95) | ALDH1A1TSHRLMNAKMT2AMEN1 | |
| Water SCHEMBL28340051 | 0.86 | ALDH1A1 (0.95) | ALDH1A1TSHRLMNAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL28555033 | 0.86 | ALDH1A1 (0.95) | ALDH1A1TSHRLMNAKMT2AMEN1 | |
| SCHEMBL29093512 | 0.86 | ALDH1A1 (0.95) | ALDH1A1TSHRLMNAKMT2AMEN1 | |
| SCHEMBL11865745 | 0.86 | ALDH1A1 (0.95) | ALDH1A1TSHRLMNAKMT2AMEN1 | |
| Fluoride SCHEMBL1403995 | 0.86 | ALDH1A1 (0.95) | ALDH1A1TSHRLMNAKMT2AMEN1 | |
| Ortho-Phthalaldehyde SCHEMBL28216717 | 0.86 | LMNA (0.68) | ALDH1A1TSHRLMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483513-B | Fluorescent molecule, preparation method and application thereof, and fluorescence detection reagent | 湖北理工学院 | 2020-12-01 | — | — | CN | disclosed |