Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | ACP3 | P15309 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28432437 | 0.79 | CNR2 (0.42) | CNR2TSHRALDH1A1HPGDALOX15 | |
| SCHEMBL28498546 | 0.78 | TDP1 (0.40) | CNR2ALDH1A1ALOX15TDP1CYP2A6 | |
| SCHEMBL28496430 | 0.77 | LMNA (0.37) | TSHRTAAR1 | |
| SCHEMBL28599439 | 0.74 | TSHR (0.42) | TSHRTDP1SMN1; SMN2 | |
| SCHEMBL28604372 | 0.73 | ALDH1A1 (0.37) | ALDH1A1TAAR1 | |
| SCHEMBL28504150 | 0.73 | CSNK1E (0.38) | CNR2ALDH1A1HTR2A | |
| SCHEMBL28920060 | 0.72 | — | — | |
| SCHEMBL28507149 | 0.72 | CSNK1E (0.41) | CNR2ALDH1A1HTR2ASMN1; SMN2 | |
| SCHEMBL7813917 | 0.72 | CNR2 (0.47) | CNR2TSHRALDH1A1HPGDANPEP | |
| SCHEMBL28505856 | 0.72 | CSNK1E (0.41) | CNR2ALDH1A1HTR2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109111333-B | Chiral gem-disilyl alkane compound and synthesis method and application thereof | 浙江大学 | 2021-01-08 | — | — | CN | disclosed |