Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21997073 | 0.80 | PTGS2 (0.39) | KDM4EMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL21069356 | 0.76 | VHL (0.35) | KDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL21069305 | 0.74 | KCNJ1 (0.44) | MEN1NPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL21070749 | 0.74 | PARP1 (0.34) | KDM4ENPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL21069438 | 0.71 | PTGS1 (0.42) | KDM4EMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL21071184 | 0.66 | MYC (0.39) | KDM4EMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL21070176 | 0.65 | MAPK1 (0.43) | KDM4ENPC1ALDH1A1MAPTRAB9A | |
| SCHEMBL23808019 | 0.61 | RECQL (0.35) | KDM4ENPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL27676382 | 0.60 | ESR2 (0.47) | MEN1NPC1MAPTRAB9AKMT2A | |
| SCHEMBL533508 | 0.58 | TDO2 (0.40) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423427-A | IRAK degrading agents and uses thereof | 凯麦拉医疗公司 | 2021-09-21 | — | — | CN | disclosed |
| CN-112105385-A | IRAK degrading agents and uses thereof | 凯麦拉医疗公司 | 2020-12-18 | — | — | CN | disclosed |