Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.49 |
| ▸ | LOX | P28300 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30566711 | 1.00 | ALOX5 (0.49) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL4954902 | 0.87 | TAS1R3 (0.50) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL27587691 | 0.87 | TAS1R3 (0.50) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL29412001 | 0.86 | BCL2L1 (0.47) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL44083 | 0.86 | BCL2L1 (0.47) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL731453 | 0.86 | BCL2L1 (0.47) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL44082 | 0.86 | BCL2L1 (0.47) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL5263311 | 0.79 | CYP2A6 (0.49) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL1259274 | 0.76 | HDAC3 (0.50) | ALOX5CYP1A2PTGESLMNALTA4H | |
| SCHEMBL22150086 | 0.75 | POLB (0.40) | LMNAGAABCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115477634-A | Compound for analgesia and medical application thereof | 中国人民解放军军事科学院军事医学研究院 | 2022-12-16 | — | — | CN | disclosed |
| CN-115433160-A | Analgesic active compound and medical application thereof | 中国人民解放军军事科学院军事医学研究院 | 2022-12-06 | — | — | CN | disclosed |