Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.65 |
| ▸ | PARP1 | P09874 | 3/20 | 0.56 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.54 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | AHR | P35869 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | NNMT | P40261 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL129457 | 1.00 | P2RX7 (0.65) | P2RX7PARP1MKNK1MKNK2RAB9A | |
| Hydrochloric Acid SCHEMBL5010797 | 0.98 | P2RX7 (0.62) | P2RX7PARP1MKNK1MKNK2RAB9A | |
| Fluoride SCHEMBL22032488 | 0.98 | P2RX7 (0.62) | P2RX7PARP1MKNK1MKNK2RAB9A | |
| Ammonia Solution, Strong SCHEMBL28560460 | 0.98 | P2RX7 (0.62) | P2RX7PARP1MKNK1MKNK2RAB9A | |
| Hydrochloric Acid SCHEMBL3086243 | 0.98 | P2RX7 (0.62) | P2RX7PARP1MKNK1MKNK2RAB9A | |
| SCHEMBL28331539 | 0.98 | P2RX7 (0.62) | P2RX7PARP1MKNK1MKNK2RAB9A | |
| SCHEMBL22032484 | 0.94 | P2RX7 (0.59) | P2RX7PARP1MKNK1MKNK2RAB9A | |
| Cyanide SCHEMBL28204544 | 0.94 | P2RX7 (0.59) | P2RX7PARP1MKNK1MKNK2RAB9A | |
| SCHEMBL29082826 | 0.93 | P2RX7 (0.62) | P2RX7PARP1MKNK1MKNK2RAB9A | |
| SCHEMBL22032483 | 0.91 | P2RX7 (0.56) | P2RX7PARP1MKNK1MKNK2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638045-B1 | AMINOALCOHOL SUBSTITUTED 2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLINE DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS AND DISEASES ASSOCIATED WITH ANGIOGENESIS | BAYER IP GMBH (DE) | 2022-08-31 | — | — | EP | claimed |
| EP-4551566-A1 | NEW SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | Les Laboratoires Servier (FR) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024008941-A1 | NEW SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS | LES LABORATOIRES SERVIER (FR) | 2024-01-11 | — | — | WO | disclosed |
| CN-110484604-B | In-situ cell RNA tailing and structure imaging method | 西安交通大学 | 2021-01-19 | — | — | CN | disclosed |