SCHEMBL129457

SCHEMBL129457

Cc1ncccc1C(N)=O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.65
PARP1 P09874 3/20 0.56
MKNK1 Q9BUB5 1/20 0.54
MKNK2 Q9HBH9 1/20 0.54
RAB9A P51151 3/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
MAPT P10636 3/20 0.54
NPC1 O15118 1/20 0.54
AHR P35869 1/20 0.54
KDM4E B2RXH2 4/20 0.51
ALDH1A1 P00352 3/20 0.51
HPGD P15428 2/20 0.51
HSD17B10 Q99714 1/20 0.51
NAPRT Q6XQN6 1/20 0.47
NNMT P40261 1/20 0.46
TDP1 Q9NUW8 2/20 0.46
SIRT3 Q9NTG7 1/20 0.46
HTT P42858 1/20 0.45
CYP3A4 P08684 1/20 0.44
ALOX15 P16050 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28905992 1.00 P2RX7 (0.65) P2RX7PARP1MKNK1MKNK2RAB9A
Hydrochloric Acid SCHEMBL5010797 0.98 P2RX7 (0.62) P2RX7PARP1MKNK1MKNK2RAB9A
Fluoride SCHEMBL22032488 0.98 P2RX7 (0.62) P2RX7PARP1MKNK1MKNK2RAB9A
Ammonia Solution, Strong SCHEMBL28560460 0.98 P2RX7 (0.62) P2RX7PARP1MKNK1MKNK2RAB9A
Hydrochloric Acid SCHEMBL3086243 0.98 P2RX7 (0.62) P2RX7PARP1MKNK1MKNK2RAB9A
SCHEMBL28331539 0.98 P2RX7 (0.62) P2RX7PARP1MKNK1MKNK2RAB9A
SCHEMBL22032484 0.94 P2RX7 (0.59) P2RX7PARP1MKNK1MKNK2RAB9A
Cyanide SCHEMBL28204544 0.94 P2RX7 (0.59) P2RX7PARP1MKNK1MKNK2RAB9A
SCHEMBL29082826 0.93 P2RX7 (0.62) P2RX7PARP1MKNK1MKNK2RAB9A
SCHEMBL22032483 0.91 P2RX7 (0.56) P2RX7PARP1MKNK1MKNK2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1697 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106725-A1 CHLOROPHYLL DERIVATIVES, CAROTENOID DERIVATIVES, AND DIETARY SUPPLEMENTS FOR HUMAN OCULAR HEALTH AND VISUAL PERFORMANCE RETINABIO, INC. (US) 2026-05-21 WO claimed
EP-4580589-A1 USE OF A COMPOSITION FOR BOOSTING SKIN'S NIGHT REPAIR ASSOCIATED FUNCTIONS Unilever IP Holdings B.V. (NL) 2025-07-09 EP claimed
EP-4577545-A1 TYK2 INHIBITORS AND USES THEREOF Sudo Biosciences Limited (GB) 2025-07-02 EP claimed
US-20250161201-A1 COSMETIC COMPOSITION THE BOOTS COMPANY PLC (GB) 2025-05-22 US claimed
US-12281094-B2 Preparation method of racemic nicotine SHENZHEN ZINWI BIO-TECH CO., LTD (CN) 2025-04-22 US claimed
CN-119654130-A Use of a composition for enhancing night repair related functions of skin 联合利华知识产权控股有限公司 2025-03-18 CN claimed
EP-4501928-A1 THIAZOLE DERIVATIVE COMPOUND AND USES THEREOF Autotelic Bio Inc. (KR) 2025-02-05 EP claimed
US-12180185-B2 Compound as protein kinase inhibitor, and pharmaceutical composition comprising thereof HK INNO.N CORPORATION (KR) 2024-12-31 US claimed
CN-119110720-A Cosmetic composition 布茨公司 2024-12-10 CN claimed
US-20240390256-A1 A DEODORANT COMPOSITION CONOPCO, INC., D/B/A UNILEVER (US) 2024-11-28 US claimed
WO-2001078648-A2 6-METHYLNICOTINAMIDE DERIVATIVES AS ANTIVIRAL AGENTS DONG WHA PHARM. IND. CO., LTD. (KR) 2001-10-25 WO claimed
EP-1123039-A1 METHOD FOR NON-INVASIVE BLOOD ANALYTE MEASUREMENT WITH IMPROVED OPTICAL INTERFACE Rio Grande Medical Technologies, Inc. (US) 2001-08-16 EP claimed
US-6240306-B1 Method and apparatus for non-invasive blood analyte measurement with fluid compartment equilibration RIO GRANDE MEDICAL TECHNOLOGIES, INC. 2001-05-29 US claimed
WO-2001001852-A1 METHOD AND APPARATUS FOR NON-INVASIVE BLOOD ANALYTE MEASUREMENT RIO GRANDE MEDICAL TECHNOLOGIES, INC. (US) 2001-01-11 WO claimed
US-6152876-A Method for non-invasive blood analyte measurement with improved optical interface RIO GRANDE MEDICAL TECHNOLOGIES, INC. (US) 2000-11-28 US claimed
EP-1017390-A2 COMBINATIONS OF HMG-COA INHIBITORS AND NICOTINIC ACID COMPOUNDS AND METHODS FOR TREATING HYPERLIPIDEMIA ONCE A DAY AT NIGHT KOS PHARMACEUTICALS, INC. (US) 2000-07-12 EP claimed
WO-2000022982-A1 METHOD FOR NON-INVASIVE BLOOD ANALYTE MEASUREMENT WITH IMPROVED OPTICAL INTERFACE RIO GRANDE MEDICAL TECHNOLOGIES, INC. (US) 2000-04-27 WO claimed
US-5872104-A BACTERICIDES AND RESISTANT BACTERIA WITH METHYLATION INHIBITORS ORIDIGM CORPORATION (US) 1999-02-16 US claimed
WO-1999006035-A2 COMBINATIONS OF HMG-CoA REDUCTASE INHIBITORS AND NICOTINIC ACID COMPOUNDS AND METHODS FOR TREATING HYPERLIPIDEMIA ONCE A DAY AT NIGHT KOS PHARMACEUTICALS, INC. (US) 1999-02-11 WO claimed
WO-1996020010-A1 COMBINATION FOR REDUCING ANTIMICROBIAL RESISTANCE USING A METHYLATION INHIBITOR IN COMBINATION WITH AN ANTIBIOTIC ORIDIGM CORPORATION (US) 1996-07-04 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12281094-B2 Preparation method of racemic nicotine NNMT, NAPRT, ADH1C P2RX7 2932/4885PARP1 1878/4885MKNK1 2769/4885
US-20250161201-A1 COSMETIC COMPOSITION CYP19A1, SHBG, HSD17B11 P2RX7 2831/4885PARP1 4749/4885MKNK1 2346/4885
US-12180185-B2 Compound as protein kinase inhibitor, and pharmaceutical composition comprising thereof MAP3K20, MAP3K1, MAP3K15 P2RX7 2697/4885PARP1 1984/4885MKNK1 49/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.