Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | GALR3 | O60755 | 2/20 | 0.44 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | UBE2N | P61088 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29940885 | 1.00 | EPHX2 (0.57) | EPHX2HPGDHTTHSD17B10APP | |
| SCHEMBL2769062 | 0.76 | EPHX2 (0.68) | EPHX2APPALDH1A1KCNA5KMT2A | |
| SCHEMBL28906172 | 0.74 | SMN1; SMN2 (0.47) | KDM4EKCNA5KMT2ALMNAMEN1 | |
| SCHEMBL2769744 | 0.72 | EPHX2 (1.00) | EPHX2APPKCNA5 | |
| SCHEMBL29941215 | 0.71 | CHRNA7 (0.48) | EPHX2HPGDHSD17B10ALDH1A1KDM4E | |
| SCHEMBL28906139 | 0.71 | CHRNA7 (0.48) | EPHX2HPGDHSD17B10ALDH1A1KDM4E | |
| SCHEMBL2769999 | 0.71 | MAOB (0.54) | EPHX2HPGDHTTALDH1A1KDM4E | |
| SCHEMBL13146632 | 0.71 | EPHX2 (0.51) | EPHX2HPGDHTTHSD17B10APP | |
| SCHEMBL2768006 | 0.71 | EPHX2 (0.72) | EPHX2HTTKCNA5KMT2AMEN1 | |
| SCHEMBL13180234 | 0.71 | EPHX2 (0.64) | EPHX2HTTKCNA5KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109006-A | 3-substituted-1, 2-benzoxazine-4-ketone compound and preparation method thereof | 上海大学 | 2022-09-27 | — | — | CN | disclosed |