Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.47 |
| ▸ | TP53 | P04637 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.39 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2768875 | 0.75 | SMN1; SMN2 (0.53) | SMN1; SMN2TP53MAPTKDM4ETSHR | |
| SCHEMBL28906138 | 0.74 | EPHX2 (0.57) | SMN1; SMN2MAPTKDM4ETSHRKMT2A | |
| SCHEMBL29940885 | 0.74 | EPHX2 (0.57) | SMN1; SMN2MAPTKDM4ETSHRKMT2A | |
| SCHEMBL9828963 | 0.74 | KCNA5 (0.55) | SMN1; SMN2TP53MAPTTSHRKCNA5 | |
| SCHEMBL6995111 | 0.73 | SMN1; SMN2 (0.59) | SMN1; SMN2TP53MAPTKDM4EKMT2A | |
| SCHEMBL6990028 | 0.70 | SMN1; SMN2 (0.50) | SMN1; SMN2TP53MAPTKDM4ELMNA | |
| SCHEMBL2768876 | 0.69 | TP53 (0.52) | SMN1; SMN2TP53MAPTTSHRHIF1A | |
| SCHEMBL6986778 | 0.69 | MAPT (0.48) | SMN1; SMN2TP53MAPTKDM4ELMNA | |
| SCHEMBL29940739 | 0.68 | FAAH (0.46) | SMN1; SMN2TP53MAPTKDM4ETSHR | |
| SCHEMBL28906154 | 0.68 | FAAH (0.46) | SMN1; SMN2TP53MAPTKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109006-B | Preparation method of 3-substituted-1, 2-benzoxazine-4-ketone compound | 上海大学 | 2025-03-14 | — | — | CN | disclosed |
| CN-115109006-A | 3-substituted-1, 2-benzoxazine-4-ketone compound and preparation method thereof | 上海大学 | 2022-09-27 | — | — | CN | disclosed |