Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.48 |
| ▸ | HTR3A | P46098 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29941215 | 1.00 | CHRNA7 (0.48) | CHRNA7HTR3AHIF1AKDM4EHSD17B10 | |
| SCHEMBL29940885 | 0.71 | EPHX2 (0.57) | KDM4EHSD17B10SMN1; SMN2CYP3A4CYP1A2 | |
| SCHEMBL28906138 | 0.71 | EPHX2 (0.57) | KDM4EHSD17B10SMN1; SMN2CYP3A4CYP1A2 | |
| SCHEMBL7893855 | 0.69 | IRAK4 (0.51) | CHRNA7HTR3AHIF1AHSD17B10SMN1; SMN2 | |
| SCHEMBL2770375 | 0.69 | HIF1A (0.48) | CHRNA7HTR3AHIF1AKDM4ESMN1; SMN2 | |
| SCHEMBL17404483 | 0.68 | SMN1; SMN2 (0.56) | CHRNA7HTR3AHIF1ASMN1; SMN2TP53 | |
| SCHEMBL28970332 | 0.68 | KAT6A (0.48) | CHRNA7HTR3AHIF1ASMN1; SMN2TP53 | |
| SCHEMBL6439681 | 0.67 | MAOA (0.48) | HIF1AKDM4EHSD17B10SMN1; SMN2CYP3A4 | |
| SCHEMBL28906146 | 0.67 | KDM4E (0.48) | HIF1AKDM4EHSD17B10SMN1; SMN2CYP3A4 | |
| SCHEMBL29940757 | 0.67 | KDM4E (0.48) | HIF1AKDM4EHSD17B10SMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109006-A | 3-substituted-1, 2-benzoxazine-4-ketone compound and preparation method thereof | 上海大学 | 2022-09-27 | — | — | CN | disclosed |