Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4291234 | 0.80 | SMN1; SMN2 (0.51) | — | |
| SCHEMBL14736717 | 0.73 | LMNA (0.49) | LMNAPTGES | |
| SCHEMBL14736718 | 0.68 | NPC1 (0.50) | LMNAPTGES | |
| SCHEMBL28937924 | 0.66 | — | — | |
| SCHEMBL25045436 | 0.64 | LMNA (0.45) | LMNA | |
| SCHEMBL25045051 | 0.62 | PTGER4 (0.37) | LMNAPTGES | |
| SCHEMBL1590278 | 0.61 | — | — | |
| SCHEMBL1412412 | 0.60 | NPC1 (0.47) | LMNAPTGES | |
| SCHEMBL21228674 | 0.60 | NPC1 (0.56) | LMNAPTGES | |
| SCHEMBL6570768 | 0.58 | KDM4E (0.44) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4149933-A1 | NEW TRIAZOLYL DERIVATIVES AS GABA A ALPHA5 PAM | F. Hoffmann-La Roche AG (CH) | 2023-03-22 | — | — | EP | disclosed |
| CN-115461337-A | Novel triazolyl derivatives as GABA A alpha 5 PAM | 豪夫迈·罗氏有限公司 | 2022-12-09 | — | — | CN | disclosed |