SCHEMBL28906213

SCHEMBL28906213

CCc1nccn1-n1c(=O)[nH]c(=O)[nH]c1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 9/20 0.40
PDE4B Q07343 9/20 0.40
PDE4C Q08493 9/20 0.40
PDE4D Q08499 9/20 0.40
ALPG P10696 2/20 0.34
PLAA Q9Y263 1/20 0.34
ALPL P05186 1/20 0.33
PDE3B Q13370 2/20 0.33
PDE3A Q14432 2/20 0.33
TYMP P19971 1/20 0.33
KMT2A Q03164 1/20 0.32
PDE2A O00408 1/20 0.31
PDE6D O43924 1/20 0.31
PDE8A O60658 1/20 0.31
PDE5A O76074 1/20 0.31
PDE9A O76083 1/20 0.31
PDE8B O95263 1/20 0.31
PDE6A P16499 1/20 0.31
PDE6G P18545 1/20 0.31
PDE6B P35913 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28882537 0.80 PDE4A (0.32) PDE4APDE4BPDE4CPDE4DALPG
SCHEMBL27859326 0.77 PDE4A (0.38) PDE4APDE4BPDE4CPDE4DPDE3B
SCHEMBL27655569 0.74 TYMP (0.41) TYMP
SCHEMBL28576509 0.67 ALDH1A1 (0.41) ALPGPLAAALPLKMT2ATSHR
SCHEMBL28319736 0.64 ALPG (0.32) ALPGPLAAALPLTSHR
SCHEMBL27469745 0.63 ALPG (0.33) ALPGPLAAALPLTSHR
SCHEMBL28746087 0.62 ALPG (0.41) PDE4APDE4BPDE4CPDE4DALPG
SCHEMBL48663 0.61
SCHEMBL28474467 0.61 TSHR (0.33) ALPGPLAAALPLKMT2ATSHR
SCHEMBL9062088 0.61 IDH1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115279808-A Resin material and multilayer printed wiring board 积水化学工业株式会社 2022-11-01 CN disclosed