Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 2/20 | 0.33 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | QPCT | Q16769 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28106054 | 0.80 | TBXAS1 (0.42) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL28319736 | 0.75 | ALPG (0.32) | ALPGPLAAALPLALDH1A1CYP1A2 | |
| SCHEMBL27779486 | 0.75 | TSHR (0.33) | TP53ALDH1A1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL27895939 | 0.75 | CYP2E1 (0.35) | ALDH1A1CYP3A4CYP19A1NFKB1QPCT | |
| SCHEMBL28576509 | 0.71 | ALDH1A1 (0.41) | ALPGPLAAALPLALDH1A1CYP1A2 | |
| SCHEMBL28474467 | 0.68 | TSHR (0.33) | ALPGPLAAALPLALDH1A1TSHR | |
| SCHEMBL8891386 | 0.67 | CYP19A1 (0.31) | CYP19A1 | |
| SCHEMBL544751 | 0.67 | ALDH1A1 (0.31) | ALDH1A1CYP11B1 | |
| SCHEMBL1412677 | 0.64 | NFKB1 (0.47) | ALDH1A1CYP3A4CYP19A1NFKB1QPCT | |
| SCHEMBL28906213 | 0.63 | PDE4A (0.40) | ALPGPLAAALPLTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1147251-A | Tetrasubstd. imidazole derivs., method for preparing same, resulting intermediates, use thereof as drug, and pharmaceutical composition contg. same | ROUSSEL UCLAF (FR) | 1997-04-09 | — | — | CN | disclosed |