Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7192713 | 0.88 | TSHR (0.52) | ALDH1A1MAOBMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL28104220 | 0.86 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3 | |
| SCHEMBL27564805 | 0.79 | ALDH1A1 (0.48) | ALDH1A1MAOBMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL9718961 | 0.78 | ALDH1A1 (0.52) | ALDH1A1MAPK1L3MBTL1SLC6A2SLC6A3 | |
| SCHEMBL7930837 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MAOBMAPK1L3MBTL1SLC6A2 | |
| Acetic Acid SCHEMBL7053200 | 0.78 | ALDH1A1 (0.61) | ALDH1A1MAOBMAPK1L3MBTL1SLC6A2 | |
| Acetic Acid SCHEMBL4466285 | 0.77 | TSHR (0.71) | ALDH1A1MAOBMAPK1L3MBTL1SLC6A2 | |
| Acetic Acid SCHEMBL28710458 | 0.77 | TSHR (0.71) | ALDH1A1MAOBMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL12223141 | 0.77 | ALDH1A1 (0.55) | ALDH1A1MAOBMAPK1L3MBTL1SLC6A2 | |
| SCHEMBL6679251 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MAOBMAPK1L3MBTL1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115443174-B | Cosmetic composition containing low molecular weight amorphous polylactic acid resin | 自然工作有限责任公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-115443174-A | Cosmetic composition containing low molecular weight amorphous polylactic acid resin | 自然工作有限责任公司 | 2022-12-06 | — | — | CN | disclosed |