Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.54 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | BRD4 | O60885 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27437769 | 0.85 | KDR (0.56) | KDRCHEK1KDM4EMAPTHPGD | |
| SCHEMBL31310116 | 0.84 | KDR (0.54) | KDRCHEK1KDM4EMAPTHPGD | |
| SCHEMBL2860216 | 0.84 | KDR (0.54) | KDRCHEK1KDM4EMAPTHPGD | |
| SCHEMBL11365957 | 0.84 | KDR (0.54) | KDRCHEK1KDM4EMAPTHPGD | |
| SCHEMBL22230600 | 0.84 | KDM4E (0.48) | KDRCHEK1KDM4EMAPTHPGD | |
| SCHEMBL8734933 | 0.83 | KDM4E (0.57) | KDRCHEK1KDM4EMAPTHPGD | |
| SCHEMBL6440320 | 0.83 | MEN1 (0.51) | KDRCHEK1KDM4EMAPTHPGD | |
| SCHEMBL4623053 | 0.81 | ESR1 (0.53) | KDRCHEK1KDM4EMAPTHPGD | |
| SCHEMBL5716844 | 0.79 | KDR (0.49) | KDRCHEK1KDM4EMAPTHPGD | |
| SCHEMBL29736523 | 0.79 | RAB9A (0.53) | KDRCHEK1KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112074265-A | Titanium dioxide | 威纳特德国有限公司 | 2020-12-11 | — | — | CN | disclosed |