Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 3/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30064624 | 0.85 | KDM4E (0.57) | KDM4EMAPTALDH1A1RAB9AMEN1 | |
| SCHEMBL28545417 | 0.85 | KDM4E (0.57) | KDM4EMAPTALDH1A1RAB9AMEN1 | |
| SCHEMBL26087356 | 0.84 | PRMT5 (0.45) | KDM4EMAPTALDH1A1RAB9AMEN1 | |
| SCHEMBL26086870 | 0.84 | F3 (0.47) | KMT2ASLC6A3SLC6A4SLC6A2 | |
| SCHEMBL28906323 | 0.83 | KDR (0.54) | KDM4EMAPTALDH1A1RAB9AMEN1 | |
| SCHEMBL11358136 | 0.83 | KDM4E (0.51) | KDM4EMAPTALDH1A1RAB9AMEN1 | |
| SCHEMBL30638485 | 0.83 | SLC6A3 (0.52) | KDM4EALDH1A1MEN1HPGDKMT2A | |
| SCHEMBL27437769 | 0.81 | KDR (0.56) | KDM4EMAPTALDH1A1RAB9AMEN1 | |
| SCHEMBL11365957 | 0.80 | KDR (0.54) | KDM4EMAPTALDH1A1RAB9AMEN1 | |
| SCHEMBL2860216 | 0.80 | KDR (0.54) | KDM4EMAPTALDH1A1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0809622-A4 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS NOVA INC (US) | 1998-07-08 | — | — | EP | disclosed |
| EP-0809622-A1 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS NOVA INC. (US) | 1997-12-03 | — | — | EP | disclosed |
| WO-1996025383-A1 | ANTI-INFLAMMATORY BENZOIC ACID DERIVATIVES | SCIOS NOVA INC. (US) | 1996-08-22 | — | — | WO | disclosed |