Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL12 | P48061 | 8/20 | 0.85 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.71 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.67 |
| ▸ | TUBB | P07437 | 1/20 | 0.67 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.67 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.67 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.67 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.67 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.67 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.67 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.67 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.67 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.67 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.67 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.67 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.67 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.67 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.66 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598880 | 0.90 | TNFRSF1A (0.79) | CXCL12ABCG2TUBB4ATUBBTUBA3C | |
| SCHEMBL5598882 | 0.90 | TNFRSF1A (0.79) | CXCL12ABCG2TUBB4ATUBBTUBA3C | |
| SCHEMBL32681387 | 0.90 | TNFRSF1A (0.79) | CXCL12ABCG2TUBB4ATUBBTUBA3C | |
| SCHEMBL5598901 | 0.90 | CXCL12 (0.82) | CXCL12ABCG2TUBB4ATUBBTUBA3C | |
| SCHEMBL5598905 | 0.90 | CXCL12 (0.82) | CXCL12ABCG2TUBB4ATUBBTUBA3C | |
| SCHEMBL28906339 | 0.89 | CXCL12 (0.71) | CXCL12ABCG2TUBB4ATUBBTUBA3C | |
| SCHEMBL11937154 | 0.89 | CXCL12 (0.85) | CXCL12ABCG2TUBB4ATUBBTUBA3C | |
| SCHEMBL8461357 | 0.89 | ABCG2 (0.88) | CXCL12ABCG2TNFRSF1A | |
| SCHEMBL8461354 | 0.89 | ABCG2 (0.88) | CXCL12ABCG2TNFRSF1A | |
| SCHEMBL3061450 | 0.88 | CXCL12 (0.85) | CXCL12ABCG2TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304513-A | Chalcone derivative with anti-inflammatory activity and synthesis method and application thereof | 湖北科技学院 | 2022-11-08 | — | — | CN | disclosed |