Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL12 | P48061 | 1/20 | 0.71 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.69 |
| ▸ | PDE4A | P27815 | 1/20 | 0.67 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.67 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.67 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.65 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.64 |
| ▸ | P4HB | P07237 | 2/20 | 0.64 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.64 |
| ▸ | TUBB | P07437 | 1/20 | 0.64 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.64 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.64 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.64 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.64 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.64 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.64 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.64 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.64 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28906331 | 0.89 | CXCL12 (0.85) | CXCL12ABCG2MKNK2TNFRSF1ATUBB4A | |
| SCHEMBL8461357 | 0.89 | ABCG2 (0.88) | CXCL12ABCG2PDE4APDE4BPDE4C | |
| SCHEMBL8461354 | 0.89 | ABCG2 (0.88) | CXCL12ABCG2PDE4APDE4BPDE4C | |
| SCHEMBL25196076 | 0.85 | TUBB1 (0.79) | CXCL12ABCG2PDE4APDE4BPDE4C | |
| SCHEMBL30384079 | 0.85 | TUBB1 (0.79) | CXCL12ABCG2PDE4APDE4BPDE4C | |
| SCHEMBL30383389 | 0.83 | CTSL (0.74) | CXCL12ABCG2P4HBTUBB4ATUBB | |
| SCHEMBL6009747 | 0.83 | ABCG2 (0.80) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29960098 | 0.83 | ABCG2 (0.80) | ABCG2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL25210464 | 0.83 | CTSL (0.74) | CXCL12ABCG2P4HBTUBB4ATUBB | |
| SCHEMBL25184983 | 0.82 | CTSL (0.76) | CXCL12ABCG2PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304513-A | Chalcone derivative with anti-inflammatory activity and synthesis method and application thereof | 湖北科技学院 | 2022-11-08 | — | — | CN | disclosed |