Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL12 | P48061 | 9/20 | 0.82 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.82 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.82 |
| ▸ | TUBB | P07437 | 1/20 | 0.82 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.82 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.82 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.82 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.82 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.82 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.82 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.82 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.82 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.82 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.82 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.82 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.82 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.82 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.80 |
| ▸ | PDE4A | P27815 | 1/20 | 0.77 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598901 | 1.00 | CXCL12 (0.82) | CXCL12ABCG2TUBB4ATUBBTUBA3C | |
| SCHEMBL12677857 | 0.95 | CXCL12 (0.89) | CXCL12ABCG2TUBB4ATUBBTUBA3C | |
| SCHEMBL30384490 | 0.95 | CXCL12 (0.89) | CXCL12ABCG2TUBB4ATUBBTUBA3C | |
| SCHEMBL25193952 | 0.95 | CXCL12 (0.89) | CXCL12ABCG2TUBB4ATUBBTUBA3C | |
| SCHEMBL17227545 | 0.92 | CXCL12 (0.77) | CXCL12ABCG2TUBB4ATUBBTUBA3C | |
| SCHEMBL30383354 | 0.91 | CAPN1 (0.82) | CXCL12TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL30383698 | 0.91 | CAPN1 (0.82) | CXCL12TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL15288998 | 0.91 | TUBB4A (0.82) | CXCL12ABCG2TUBB4ATUBBTUBA3C | |
| SCHEMBL597849 | 0.91 | CAPN1 (0.82) | CXCL12TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL597850 | 0.91 | CAPN1 (0.82) | CXCL12TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2754712-B1 | MUTANT ENDOGLUCANASE | TORAY INDUSTRIES (JP) | 2017-10-04 | — | — | EP | disclosed |
| US-20160039734-A1 | THERAPEUTIC CURCUMIN DERIVATIVES | STC UNM (US) | 2016-02-11 | — | — | US | disclosed |
| US-9193963-B2 | Mutant endoglucanase | TORAY INDUSTRIES, INC. (JP) | 2015-11-24 | — | — | US | disclosed |
| US-9187397-B2 | Therapeutic curcumin derivatives | STC.UNM (US) | 2015-11-17 | — | — | US | disclosed |
| US-20150011494-A1 | THERAPEUTIC CURCUMIN DERIVATIVES | STC.UNM | 2015-01-08 | — | — | US | disclosed |
| US-8841326-B2 | Therapeutic curcumin derivatives | STC.UNM (US) | 2014-09-23 | — | — | US | disclosed |
| US-20140178947-A1 | MUTANT ENDOGLUCANASE | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2014-06-26 | — | — | US | disclosed |
| US-20070060644-A1 | Therapeutic curcumin derivatives | STC.UNM | 2007-03-15 | — | — | US | disclosed |
| US-20060276536-A1 | Cancer treatment using curcumin derivatives | STC.UNM | 2006-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160039734-A1 | THERAPEUTIC CURCUMIN DERIVATIVES | FABP2, GLS2, FABP1 | CXCL12 2113/4885ABCG2 2380/4885TUBB4A 226/4885 |
| US-20070060644-A1 | Therapeutic curcumin derivatives | FABP2, GLS2, FABP1 | CXCL12 2113/4885ABCG2 2380/4885TUBB4A 226/4885 |
| US-20150011494-A1 | THERAPEUTIC CURCUMIN DERIVATIVES | FABP2, GLS2, FABP1 | CXCL12 2113/4885ABCG2 2380/4885TUBB4A 226/4885 |
| US-20060276536-A1 | Cancer treatment using curcumin derivatives | BRCA1, VHL, TP53 | CXCL12 2895/4885ABCG2 4415/4885TUBB4A 820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.