Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29160835 | 0.89 | ADRA2A (0.51) | ADRA2AADRA2BADRA2CCYP2D6ADRA1D | |
| SCHEMBL14282042 | 0.79 | DRD2 (0.52) | ALDH1A1KDM4ENPC1RAB9AHPGD | |
| SCHEMBL38654618 | 0.74 | ADRA2A (0.51) | ADRA2AADRA2BADRA2CCYP2D6ADRA1D | |
| SCHEMBL26027881 | 0.74 | ADRA2A (0.58) | ADRA2AADRA2BADRA2CCYP2D6ADRA1D | |
| SCHEMBL4601564 | 0.70 | CYP2A6 (0.52) | ADRA2AADRA2BADRA2CCYP2D6ADRA1D | |
| SCHEMBL8083358 | 0.70 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CCYP2D6ADRA1D | |
| SCHEMBL11718775 | 0.70 | ADRA2A (0.43) | ADRA2AADRA2BADRA2CCYP2D6ADRA1D | |
| Hydrochloric Acid SCHEMBL10871080 | 0.69 | NPSR1 (1.00) | ADRA2AADRA2BADRA2CCYP2D6ADRA1D | |
| SCHEMBL11714891 | 0.69 | ADRA2A (0.51) | ADRA2AADRA2BADRA2CCYP2D6ADRA1D | |
| SCHEMBL10882588 | 0.68 | ADRA2A (0.69) | ADRA2AADRA2BADRA2CCYP2D6ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427410-B | Amide or sulfonamide derivatives and application thereof | 苏州恩华生物医药科技有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-115427410-A | Amide or sulfonamide derivative and application thereof | 苏州恩华生物医药科技有限公司 | 2022-12-02 | — | — | CN | disclosed |