Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | POLQ | O75417 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30987616 | 0.86 | JMJD6 (0.39) | JMJD6PLA2G2AKDM4EASPHKDM8 | |
| SCHEMBL2022063 | 0.81 | KDM4E (0.42) | JMJD6KDM4EASPHKDM8MAPT | |
| SCHEMBL22275181 | 0.81 | KDM4E (0.49) | KDM4EMAPTTSHRALDH1A1HPGD | |
| SCHEMBL20855653 | 0.81 | POLQ (0.45) | PLA2G2AKDM4EMAPTTSHRALDH1A1 | |
| SCHEMBL24769678 | 0.81 | ALDH1A1 (0.43) | PLA2G2AKDM4EMAPTTSHRALDH1A1 | |
| SCHEMBL11414590 | 0.80 | PARP1 (0.40) | JMJD6KDM4EASPHKDM8 | |
| SCHEMBL9110478 | 0.77 | KDM4E (0.46) | KDM4EASPHKDM8MAPTTSHR | |
| SCHEMBL2025343 | 0.77 | SOS1 (0.40) | JMJD6KDM4EASPHKDM8MAPT | |
| SCHEMBL1330158 | 0.77 | KDM4E (0.45) | JMJD6KDM4EASPHKDM8MAPT | |
| SCHEMBL12192175 | 0.77 | NNMT (0.46) | JMJD6KDM4EASPHKDM8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304623-A | Pyrimido-cyclic derivative and application thereof in medicine | 四川海思科制药有限公司 | 2022-11-08 | — | — | CN | disclosed |